Citation: Yi HU, Jue CHEN, Zhang Gao LE, Zhen Chu CHEN, Qin Guo ZHENG. Organic Reactions in Ionic Liquids:An Efficient Method for the Synthesis of Phenacyl Esters by Reaction of Carboxylic Acids with α-Bromoacetophenone Promoted by Potassium Fluoride[J]. Chinese Chemical Letters, ;2005, 16(7): 903-905. shu

Organic Reactions in Ionic Liquids:An Efficient Method for the Synthesis of Phenacyl Esters by Reaction of Carboxylic Acids with α-Bromoacetophenone Promoted by Potassium Fluoride

Yi HU ^1,2, ,
Jue CHEN ¹ ,
Zhang Gao LE ^1,2,3 ,
Zhen Chu CHEN ^1,2 ,
Qin Guo ZHENG ⁴

1.
Ningbo Institute of Technology, Zhejiang University, Ningbo 315100;
2.
Department of Chemistry, Zhejiang University (Xi Xi Campus), Hangzhou 310028;
3.
Department of Applied Chemistry, East China Institute of Technology, Fuzhou 344000;
4.
Pharmaceutical Science Research Institute, Aston University, Aston Triangle, Birmingham B4 TET, UK

Received Date: 16 August 2004

An efficient method is reported for the synthesis of phenacyl esters by reaction of carboxylic acids with α-bromoacetophenone promoted by potassium fluoride in ionic liquid[Bmim]PF₆, the yield of the reaction is almost quantitative and the products are essentially pure.
- Ionic liquids,
- phenacyl esters,
- potassium fluoride
1. [1]
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2. [2]
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3. [3]
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4. [4]
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5. [5]
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6. [6]
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7. [7]
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9. [9]
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12. [12]
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13. [13]
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14. [14]
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15. [15]
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16. [16]
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17. [17]
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18. [18]
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19. [19]
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20. [20]
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