Citation: You Cheng LIU, Xin Zhu LI, Jing LI. Liquid Chromatographic Resolution of Racemic 2-Phenyl-1,1-cyclo-propanedicarbonitrile and its Analogues on Chiral Stationary Phase[J]. Chinese Chemical Letters, ;2000, 11(4): 353-356. shu

Liquid Chromatographic Resolution of Racemic 2-Phenyl-1,1-cyclo-propanedicarbonitrile and its Analogues on Chiral Stationary Phase

a Department of Chemistry, University of Science and Technology of China, Hefei 230026;
b National Laboratory of Applied Organic Chemistry and Department of Chemistry Lanzhou University, Lanzhou 730000

Received Date: 3 November 1999
Revised Date: 3 January 2000

Fund Project: Support from the National Natural Science Foundation of China is gratefully acknowledged.

Excellent resolution of racemic 2-phenyl-1,1-cyclopropanedicarbonitrile and its nine analogues was accomplished using 100-5CHI-TBB chiral stationary phase under normal-phase HPLC conditions. The influence of mobile phase and the optimum conditions for the resolution of optically active enantiomers were investigated.
- HPLC,
- chiral stationary phase,
- 2-phenyl-1,1-cyclopropanedicarbonitrile (PCN),
- chromatographic resolution
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