Citation: Hua Tingbi, Yang Qingqing, Xiao Wengjing. Recent Developments of Reactions with C, N-Cyclic Azomethine Imines[J]. Chinese Journal of Organic Chemistry, ;2020, 40(11): 3559-3595. doi: 10.6023/cjoc202006072 shu

Recent Developments of Reactions with C, N-Cyclic Azomethine Imines

Hua Tingbi ^a,b ,
Yang Qingqing ^a,b,, ,
Xiao Wengjing ^c,,

a.
Hubei Key Laboratory of Natural Products Research and Development, China Three Gorges University, Yichang, Hubei 443002
b.
Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials, College of Materials and Chemical Engineering, China Three Gorges University, Yichang, hubei 443002
c.
Key Laboratory of Pesticide&Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079

Corresponding author: Yang Qingqing, qingqing_yang@ctgu.edu.cn Xiao Wengjing, wxiao@mail.ccnu.edu.cn
Received Date: 30 June 2020
Revised Date: 4 September 2020
Available Online: 15 September 2020
Fund Project: Research Fund for Excellent Dissertation of China Three Gorges University and the Programme of Introducing Talents of Discipline to Universities D20015National Natural Science Foundation of China 21702121Open Fund from Hubei Key Laboratory of Natural Products Research and Development (China Three Gorges University) NPRD-2018010Project supported by the National Natural Science Foundation of China (No. 21702121), the Open Fund from Hubei Key Laboratory of Natural Products Research and Development (China Three Gorges University) (No. NPRD-2018010), the Research Fund for Excellent Dissertation of China Three Gorges University and the Programme of Introducing Talents of Discipline to Universities (111 Project, No. D20015)Research Fund for Excellent Dissertation of China Three Gorges University and the Programme of Introducing Talents of Discipline to Universities 111 Project

Figures(61)

Among various 1, 3-dipoles of cyclic azomethine imines, C, N-cyclic azomethine imines are the most widely used reagents in the construction of diverse tetrahydroisoquinoline derivatives. The developments of reactions with C, N-cyclic azomethine imines including [3+2], [3+3], [3+4], [5+1], [3+1] cycloaddition reactions and miscellaneous reactions are summarized. The properties of reactions, reaction processes and synthetic applications are discussed. Finally, the prospects of the reaction with this reagent are also proposed.
- 1, 3-dipole,
- azomethine imine,
- C, N-cyclic azomethine imine,
- cycloaddition reaction,
- isoquinoline derivative
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沈阳化工大学材料科学与工程学院沈阳 110142