Citation: Liu Lingling, Yang Shan, Han Yi, Dai Chenyang, Shi Daqing, Huang Zhibin, Zhao Yingsheng. Rhodium-Catalyzed ortho-Alkenylation of Phenols Directed by Acetone Oxime Ether[J]. Chinese Journal of Organic Chemistry, ;2020, 40(8): 2394-2401. doi: 10.6023/cjoc202004019 shu

Rhodium-Catalyzed ortho-Alkenylation of Phenols Directed by Acetone Oxime Ether

College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123

Corresponding author: Huang Zhibin, zbhuang@suda.edu.cn Zhao Yingsheng, yszhao@suda.edu.cn
Received Date: 13 April 2020
Revised Date: 22 May 2020
Available Online: 29 May 2020
Fund Project: National Natural Science Foundation of China 21572149Major Basic Research Project of the Natural Science Foundation of Jiangsu Higher Education Institutions 15KJA150006Project of Scientific and Technologic Infrasracture of Suzhou SZS2018201708Project supported by the National Natural Science Foundation of China (Nos. 21772139, 21572149), the Major Basic Research Project of the Natural Science Foundation of Jiangsu Higher Education Institutions (Nos. 15KJA150006, 17KJA150006), the Jiangsu Province Natural Science Found for Distinguished Young Scholars (No. BK2018g0041), the Project of Scientific and Technologic Infrasracture of Suzhou (No. SZS2018201708) and the Priority Academic Program Development of Jiangsu Higher Education Institutions ProjectJiangsu Province Natural Science Found for Distinguished Young Scholars BK2018g0041National Natural Science Foundation of China 21772139Major Basic Research Project of the Natural Science Foundation of Jiangsu Higher Education Institutions 17KJA150006

Figures(3)

A practical rhodium-catalyzed highly regioselective ortho-alkenylation of phenolic compound under the assistance of weak coordination center acetoxime ether was developed. This strategy has advantages of simple and mild reaction conditions, wide scope of substrate and high regioselectivity. This protocol provids an efficient and new method for the regioselective ortho-alkenylation of phenols.
- phenol,
- acetone oxime ether,
- alkenylation
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