Citation: Li Huaigui, Yang Peng, Xu Zheng, Du Zhengyin, Fu Ying. Cu-Catalyzed Direct Arylation of Benzothiazoles with Diaryliodonium Salts[J]. Chinese Journal of Organic Chemistry, ;2020, 40(8): 2476-2482. doi: 10.6023/cjoc202002042 shu

Cu-Catalyzed Direct Arylation of Benzothiazoles with Diaryliodonium Salts

College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070

Corresponding author: Du Zhengyin, clinton_du@126.com Fu Ying, fu_yingmail@126.com
Received Date: 29 February 2020
Revised Date: 10 May 2020
Available Online: 19 May 2020
Fund Project: The National Natural Science Foundation of China 21762040The National Natural Science Foundation of China 21762039The National Natural Science Foundation of China 21262028Project supported by the National Natural Science Foundation of China (Nos. 21262028, 21762039, 21762040)

Figures(3)

Diaryliodonium salts have low toxicity and good stability, and their mediated reactions often have advantages of mild reaction conditions and high selectivity. They have received extensive attention and have been widely used as arylating agents in organic synthesis. A simple and efficient method for the synthesis of 2-arylbenzothiazole derivatives via copper-catalyzed C-H direct arylation of benzothiazoles with diaryliodonium salts as electrophilic arylating reagents was developed. This method shows wide range of substrates, good group tolerance, simple operation and high product yields.
- benzothiazole,
- arylation,
- diaryliodonium salt,
- cross coupling,
- C-H activation
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