Citation: Wang Shoufeng, Wang Wengui. Recent Advances of the Construction of Trifluoromethylated Quaternary Carbon Center[J]. Chinese Journal of Organic Chemistry, ;2020, 40(7): 1901-1911. doi: 10.6023/cjoc202001012 shu

Recent Advances of the Construction of Trifluoromethylated Quaternary Carbon Center

Wang Shoufeng ^, ,
Wang Wengui ^,

Shandong Provincial Key Laboratory of Fluorine Chemistry and Chemical Materials, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022

Corresponding author: Wang Shoufeng, chm_wangsf@ujn.edu.cn Wang Wengui, chm_wangwg@ujn.edu.cn
Received Date: 7 January 2020
Revised Date: 24 March 2020
Available Online: 10 April 2020
Fund Project: the National Natural Science Foundation of China 31972850the Shandong Provincial Key Research Program 2019GSF108223Project supported by the National Natural Science Foundation of China (No. 31972850) and the Shandong Provincial Key Research Program (No. 2019GSF108223)

Figures(23)

Trifluoromethyl is an important group, which is often used in pharmecuticals and agrochemicals. Quaternary carbon centers are widely existed in natural products and synthetic compounds. Recently, the construction of molecules containing trifluoromethylated quaternary carbon centers has been developed rapidly. Starting with direct trifluoromethylation, new synthons and new reactions, the research progress of the synthesis of trifluoromethylated quaternary carbon centers is reviewed.
- trifluoromethyl,
- quaternary carbon center,
- research progress
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