Citation: Yang Sen, Ding Chengrong, Liu Xinghai, Weng Jianquan, Yuan Jing, Tan Chengxia. Synthesis and Herbicidal Activity of Chiral Aryloxyphenoxypropionic Amides Compounds[J]. Chinese Journal of Organic Chemistry, ;2019, 39(12): 3588-3593. doi: 10.6023/cjoc201905028 shu

Synthesis and Herbicidal Activity of Chiral Aryloxyphenoxypropionic Amides Compounds

a.
College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014
b.
College of Forestry and Biotechnology, Zhejiang Agriculture and Forestry University, Hangzhou 311300

Corresponding author: Yuan Jing, 1015251265@qq.com Tan Chengxia, tanchengxia@zjut.edu.cn
Received Date: 13 May 2019
Revised Date: 3 June 2019
Available Online: 19 December 2019
Fund Project: Project supported by the National Key R & D Program (No. 2017YFD0200507)the National Key R & D Program 2017YFD0200507

Figures(3)

In order to find pesticidal lead compounds with high herbicidal activity, a series of novel chiral aryloxyphenoxypropionic amides were designed and synthesized using the principle of active substructure combination and the technology of biological enzyme splitting. The structures of the target compounds were confirmed by ¹H NMR and HRMS. The preliminary bioassay data showed that all target compounds displayed excellent herbicidal activity and selectivity against monocotyledonous weeds. At the dosage of 150 g/ha, the target compounds showed herbicidal activity against Backmannia syzigachne, Polypogon fugax and Poa acroleuca with more than 75%. And the control effects of three compounds against Polypogon fugax Nees were 100%.
- aryloxyphenoxypropionic acids,
- herbicide,
- chirality,
- herbicidal activity,
- synthesize,
- enzyme splitting
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