Citation: Xu Jing, Fan Weigang, Popowycz Florence, Queneau Yves, Gu Yanlong. Multicomponent Reactions: A New Strategy for Enriching the Routes of Value-Added Conversions of Bio-platform Molecules[J]. Chinese Journal of Organic Chemistry, ;2019, 39(8): 2131-2138. doi: 10.6023/cjoc201904065 shu

Multicomponent Reactions: A New Strategy for Enriching the Routes of Value-Added Conversions of Bio-platform Molecules

a.
Hubei Key Laboratory of Material Chemistry and Service Failure, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China
b.
Entre National de la Recherche Scientifique, Université de Lyon, F-69622 Villeurbanne Cedex, France

Corresponding author: Gu Yanlong, klgyl@hust.edu.cn
Received Date: 26 April 2019
Revised Date: 7 July 2019
Available Online: 24 August 2019
Fund Project: Project supported by the National Natural Science Foundation of China 2171101076Project supported by the National Natural Science Foundation of China (No. 2171101076)

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Synthesis of complex molecules via multicomponent reactions (MCRs) in a one-pot reaction manner has emerged as an important means to realize the value-added conversion of cheap and easily available renewable bio-based platform molecules. The diversity and multi-functionality of these biomass-derived molecules provide a fascinating platform for establishing MCRs, and in many cases, the developed MCRs would not be attained from less functionalized substrates. This review introduces some typical examples for the conversion of biomass-derived platform compounds to high value-added products through MCRs. It mainly summarizes the MCRs developed by using polyols, dicarboxylic acids, levulinic acid and furfural derivatives as one of the starting substrates. At the end of this review, a perspective of this direction is also given.
- biomass-derived platform molecules,
- multicomponent reactions (MCRs),
- biomass valorization,
- green chemistry
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