Citation: Wang Jinglin, Shen Chengshuo, Tang Songchao, Yao Yuan. Study of Charge-Conjugated Self-Assembly Behavior of Amphiphilic Block Copolypeptides/Helicene[J]. Chinese Journal of Organic Chemistry, ;2019, 39(10): 2973-2979. doi: 10.6023/cjoc201904038 shu

Study of Charge-Conjugated Self-Assembly Behavior of Amphiphilic Block Copolypeptides/Helicene

a.
Teaching and Research Department of Polymer Materials and Engineering, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237
b.
School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240

Corresponding author: Tang Songchao, schtang@ecust.edu.cn Yao Yuan, yaoyuan@ecust.edu.cn
Received Date: 15 April 2019
Revised Date: 7 May 2019
Available Online: 21 October 2019
Fund Project: the National Natural Science Foundation of China 51573088Project supported by the National Natural Science Foundation of China (No. 51573088)

Figures(8)

Amphiphilic block copolypeptides of polyethylene glycol-b-poly(L-glutamic acid) (PEG-b-PGlu) were synthesized to self-assemble with 4-methyl-4-aza[4]helicene onium ion (Me[4]H) in water through charge-conjugation. The morphology of the assemblies was studied by varying PGlu block length, the molar ratio of Glu unit/Me[4]H and pH value. It was found that when rigid-flexible block copolymers were assembled together with small molecules which had rigid, large size and inductive effect, they would follow a completely different law from the charge-conjugated assembly of flexible macromolecules. The self-assemblies were controlled by the π-π stacking of helicene, together with the volume fraction of the hydrophobic parts and the rigidity of PGlu segments. These effects restricted each other in the assembly process. When π-π stacking was dominant, assembly morphologies with pointer-like and strip-like planar structures were obtained.
- charge-conjugated self-assembly,
- amphiphilic block copolymer,
- helicene
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