Citation: Fan Zhengning, Zhang Bo, Xi Chanjuan. NaBH₄/I₂-Mediated Efficient Iodination of Alcohols[J]. Chinese Journal of Organic Chemistry, ;2019, 39(8): 2333-2337. doi: 10.6023/cjoc201903036 shu

NaBH₄/I₂-Mediated Efficient Iodination of Alcohols

a.
Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084
b.
State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071

Corresponding author: Xi Chanjuan, cjxi@tsinghua.edu.cn
Received Date: 20 March 2019
Revised Date: 17 April 2019
Available Online: 26 August 2019
Fund Project: Project supported by the National Natural Science Foundation of China (Nos. 21871163, 91645120)the National Natural Science Foundation of China 91645120the National Natural Science Foundation of China 21871163

Figures(2)

A simple, mild, and high yielding procedure for the iodination of alcohols using a combination of NaBH₄ and I₂ is described. The effectiveness of the protocol is achieved with benzylic alcohols and primary alkylic alcohols whereas allylic and secondary alcohols are found to be unreactive.
- alcohol,
- iodide,
- sodium borohydride,
- iodination
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1.
沈阳化工大学材料科学与工程学院沈阳 110142

NaBH4/I2-Mediated Efficient Iodination of Alcohols

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通讯作者: 陈斌, bchen63@163.com

NaBH₄/I₂-Mediated Efficient Iodination of Alcohols