Citation: Yang Zhenhua, Zhu Jianan, Wen Caiyue, Ge Yingxiang, Zhao Shengyin. Recent Advances in Functionalization of Double Bond Based on Maleimides[J]. Chinese Journal of Organic Chemistry, ;2019, 39(9): 2412-2427. doi: 10.6023/cjoc201902012 shu

Recent Advances in Functionalization of Double Bond Based on Maleimides

Key Laboratory of Science and Technology of Exo-Textile, Ministry of Education, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620

Corresponding author: Zhao Shengyin, syzhao8@dhu.edu.cn
Received Date: 14 February 2019
Revised Date: 10 April 2019
Available Online: 19 September 2019
Fund Project: the Shanghai Municipal Natural Science Foundation 15ZR1401400Project supported by the Shanghai Municipal Natural Science Foundation (No. 15ZR1401400) and the National Undergraduate Training Program for Innovation and Entrepreneurship in Donghua University (2018)

Figures(7)

Maleimide, a common motif in a variety of natural alkaloids, has been extensively investigated due to its noteworthy biological activities and optical properties. Additionally, it can be transformed into many important heterocyclic frameworks such as succinimides, pyrrolidines, and 2-pyrrolidones. Thus, a great deal of attention has been focused on the development of new synthetic routes to access polyfunctionalized maleimides. In this article, the recent research progress in functionalization of double bond is reviewed based on maleimides according to Michael addition, oxidative coupling and cycloaddition reaction.
- maleimide,
- Michael addition,
- oxidative coupling,
- cycloaddition reaction
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沈阳化工大学材料科学与工程学院沈阳 110142