Citation: Wang Yunlong, Zhang Linbao, Niu Junlong, Song Maoping. Copper-Promoted Direct Nitration of Arenes Assisted by an N, O-Bidentate Directing System[J]. Chinese Journal of Organic Chemistry, ;2019, 39(6): 1761-1766. doi: 10.6023/cjoc201901015 shu

Copper-Promoted Direct Nitration of Arenes Assisted by an N, O-Bidentate Directing System

a.
College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001
b.
College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao 266042

Corresponding author: Niu Junlong, niujunlong@zzu.edu.cn Song Maoping, mpsong@zzu.edu.cn
Received Date: 11 January 2019
Revised Date: 25 February 2019
Available Online: 8 June 2019
Fund Project: the Program for Science & Technology Innovation Talents in Universities of Henan Province 19HASTIT038Project supported by the National Natural Science Foundation of China (Nos. 21772179, 21672192), the Program for Science & Technology Innovation Talents in Universities of Henan Province (No. 19HASTIT038)the National Natural Science Foundation of China 21672192the National Natural Science Foundation of China 21772179

Figures(3)

Cu(Ⅱ)-promoted C-H nitration of arenes has been disclosed with the aid of N, O-bidentate directing group. The protocol was operationally simple by using NaNO₂as the nitration source. Various amide substrates were tolerated in the reaction system, which establishes opportunities for developing simple and facile methods, and enriches the strategies to access aromatic nitro derivatives.
- C-H activation,
- bidentate direction,
- Cu-catalyzed,
- nitration
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