Citation: Wang Leilei, Bao Pengli, Liu Weiwei, Liu Sitong, Hu Changsong, Yue Huilan, Yang Daoshan, Wei Wei. Direct C-H 3-Arylation of Quinoxalin-2(H)-ones with Aryl Diazonium Salts under Visible-Light Irradiation[J]. Chinese Journal of Organic Chemistry, ;2018, 38(12): 3189-3196. doi: 10.6023/cjoc201807014 shu

Direct C-H 3-Arylation of Quinoxalin-2(H)-ones with Aryl Diazonium Salts under Visible-Light Irradiation

Wang Leilei ^a ,
Bao Pengli ^a ,
Liu Weiwei ^a ,
Liu Sitong ^a ,
Hu Changsong ^a ,
Yue Huilan ^b ,
Yang Daoshan ^a ,
Wei Wei ^a,b,,

a.
School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165
b.
Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008

Corresponding author: Wei Wei, weiweiqfnu@163.com
Received Date: 6 July 2018
Revised Date: 22 July 2018
Available Online: 22 December 2018
Fund Project: the International Cooperation Project of Qinghai Province 2018-HZ-806the International Cooperation Project of Qinghai Province 2017-HZ-806the National Natural Science Foundation of China 21302109the Natural Science Foundation of Shandong Province ZR2018MB009the Natural Science Foundation of Shandong Province ZR2016JL012the National Natural Science Foundation of China 21302110Supported by the Natural Science Foundation of Shandong Province (Nos. ZR2018MB009, ZR2016JL012), the International Cooperation Project of Qinghai Province (Nos. 2018-HZ-806, 2017-HZ-806) and the National Natural Science Foundation of China (Nos. 21302109, 21302110)

Figures(3)

A simple and practical visible-light-induced protocol has been developed for the construction of 3-arylquinoxa-lin-2(1H)-ones via Eosin Y-catalyzed direct C-H 3-arylation of quinoxalin-2(H)-ones with aryl diazonium salts at room temperature in air. The present reaction provides a cost-effective and operationally straightforward approach to the target products in moderate to good yields, and does not require any metal reagents, bases, acids, and strong oxidants.
- visible-light,
- Eosin Y catalysis,
- C-H arylation,
- aryl diazonium salt,
- 3-arylquinoxalin-2(1H)-one
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