Citation: Hou Jiao, Zhang Xinting, Yu Wenquan, Chang Junbiao. I₂-Mediated Oxidative C-O Bond Formation for the Synthesis of Isoxazoles[J]. Chinese Journal of Organic Chemistry, ;2018, 38(12): 3236-3241. doi: 10.6023/cjoc201806026 shu

I₂-Mediated Oxidative C-O Bond Formation for the Synthesis of Isoxazoles

a.
College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001

Corresponding author: Yu Wenquan, wenquan_yu@zzu.edu.cn Chang Junbiao, changjunbiao@zzu.edu.cn
Received Date: 16 June 2018
Revised Date: 2 August 2018
Available Online: 23 December 2018
Fund Project: the Outstanding Young Talent Research Fund of Zhengzhou University 1521316004the National Natural Science Foundation of China 81773570Project supported by the National Natural Science Foundation of China (Nos. 81773570, 81330075) and the Outstanding Young Talent Research Fund of Zhengzhou University (No. 1521316004)the National Natural Science Foundation of China 81330075

Figures(1)

A variety of mono-, di-, and tri-substituted (aryl, alkyl, and/or alkenyl) isoxazoles were synthesized from readily accessible α, β-unsaturated oximes via I₂-mediated oxidative C-O bond formation. The features of this synthetic approach include no use of transition metals, simple operation, mild reaction conditions, short reaction time, and broad substrate scope.
- isoxazole,
- iodine,
- α, β-unsaturated oxime,
- C-O bond formation
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沈阳化工大学材料科学与工程学院沈阳 110142

I2-Mediated Oxidative C-O Bond Formation for the Synthesis of Isoxazoles

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通讯作者: 陈斌, bchen63@163.com

I₂-Mediated Oxidative C-O Bond Formation for the Synthesis of Isoxazoles