Citation: Fang Zhixing, Liu Juyan, Qiao Yanhong. Bromodimethylsulfonium Bromide Catalyzed Synthesis of Pyrazole-Fused Isocoumarins[J]. Chinese Journal of Organic Chemistry, ;2018, 38(8): 1985-1992. doi: 10.6023/cjoc201803019 shu

Bromodimethylsulfonium Bromide Catalyzed Synthesis of Pyrazole-Fused Isocoumarins

Tianjin Key Laboratory of Structure and Performance for Functional Molecule, Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry, Ministry of Education, College of Chemistry, Tianjin Normal University, Tianjin 300387

Corresponding author: Liu Juyan, hxxyljy@mail.tjnu.edu.cn
Received Date: 14 March 2018
Revised Date: 5 May 2018
Available Online: 24 August 2018
Fund Project: the Natural Science Foundation of Tianjin City 12JCZDJC34300Project supported by the Natural Science Foundation of Tianjin City (No. 12JCZDJC34300), and the College Students' Entrepreneurship Training Program (No. 201447)the College Students' Entrepreneurship Training Program 201447

Figures(2)

A series of pyrazole-fused isocoumarins were synthesized by the reaction of ninhydrin hydrate and arylhydrazones in the presence of bromodimethylsulfonium bromide (BDMS) at room temperature. The reaction has the advantages of mild conditions, simple operation, the ready accessibility of the catalyst, and short reaction times.
- ninhydrin hydrate,
- arylhydrazones,
- pyrazole-fused isocoumarins,
- BDMS
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