Citation: Ma Nan, Zeng Xianghua. Cu₂O-Catalyzed Green Oxidative Terminal Alkynes Homocoupling without Bases[J]. Chinese Journal of Organic Chemistry, ;2018, 38(6): 1556-1561. doi: 10.6023/cjoc201712038 shu

Cu₂O-Catalyzed Green Oxidative Terminal Alkynes Homocoupling without Bases

Ma Nan ,
Zeng Xianghua ^,

College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001

Corresponding author: Zeng Xianghua, xianghuazeng@mail.zjxu.edu.cn
Received Date: 27 December 2017
Revised Date: 31 January 2018
Available Online: 11 June 2018
Fund Project: the National Natural Science Foundation of Zhejiang Province LY17B030011Project supported by the National Natural Science Foundation of Zhejiang Province (No. LY17B030011) and the Jiaxing Science and Technology Project (No. 2015AY11014)the Jiaxing Science and Technology Project 2015AY11014

Figures(4)

A high efficient method for the synthesis of 1, 3-diynes derivatives which employed terminal alkynes as the substrates and copper(I) oxide as the catalyst was developed. This method possessed the character of base-free and mild reaction conditions. The reaction mechanism was also studied. Furthermore, this reaction could be magnified to gram scale and the catalyst of copper(I) oxide could be recycled.
- copper (I) oxide,
- homocoupling,
- terminal alkynes,
- base-free
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Cu₂O-Catalyzed Green Oxidative Terminal Alkynes Homocoupling without Bases