Citation: Jiang Youhao, Lu Guolin, Peng Wen. Synthesis of Phenoxyallene-Based Amphiphilic Block Copolymer[J]. Chinese Journal of Organic Chemistry, ;2017, 37(12): 3248-3256. doi: 10.6023/cjoc201710037 shu

Synthesis of Phenoxyallene-Based Amphiphilic Block Copolymer

a.
Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062
b.
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032

Corresponding author: Peng Wen, 13061677336@163.com
Received Date: 31 October 2017
Revised Date: 9 November 2017
Available Online: 15 December 2017
Fund Project: Project supported by the National Natural Science Foundation of China (No. 21674124)the National Natural Science Foundation of China 21674124

Figures(9)

An amphiphilic triblock copolymer comprising double-bond-containing poly(phenoxyallene) (PPOA) was synthesized by a combination of conventional free radical polymerization and atom transfer radical polymerization (ATRP) via the site transformation strategy. A new bifunctional initiator containing azo and ATRP initiating groups was prepared and used for conventional free radical homopolymerization of phenoxyallene (POA) to afford a PPOA-based macroinitiator bearing ATRP initiating groups. Subsequent ATRP of hydrophilic monomer, 2-((diethylamino)ethyl methacrylate) (DEAEMA), initiated by PPOA-based macroinitiator afforded PDEAEMA-b-PPOA-b-PDEAEMA triblock copolymer. This triblock copolymer can self-assemble into micelles, and critical micelle concentration (cmc) of PDEAEMA-b-PPOA-b-PDEAEMA amphiphilic triblock copolymer in aqueous solution was determined by fluorescence probe technique. The dependence of cmc on pH and ion strength was also investigated.
- polyallene,
- block copolymer,
- bifunctional initiator,
- ATRP
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