Citation: Liao Fumin, Yu Jinsheng, Zhou Jian. Recent Advances in the Highly Stereoselective Synthesis of Tri-or Tetra-substituted Monofluoroalkenes[J]. Chinese Journal of Organic Chemistry, ;2017, 37(9): 2175-2186. doi: 10.6023/cjoc201705001 shu

Recent Advances in the Highly Stereoselective Synthesis of Tri-or Tetra-substituted Monofluoroalkenes

Liao Fumin ^a ,
Yu Jinsheng ^a,, ,
Zhou Jian ^a,b,,

a.
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062
b.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032

Corresponding author: Yu Jinsheng, yujinsheng2011@163.com Zhou Jian, jzhou@chem.ecnu.edu.cn
Received Date: 1 May 2017
Revised Date: 28 June 2017
Available Online: 7 September 2017
Fund Project: Project supported by the National Natural Science Foundation of China (No. 21472049)the National Natural Science Foundation of China 21472049

Figures(25)

Monofluoroalkenes have found applications in many areas of research, including the design and development new materials and drug. The highly stereoselective synthesis of this privileged structural motif has attracted great synthetic attention. This review summarizes recent progresses in highly stereoselective synthesis of monofluoroalkenes from aldehydes, ketones and diazo compounds, other substrates such as alkynes, alkenyl metallic species and alkenes are also included. The advantages and disadvantages of different methods are discussed.
- monofluoroalkene,
- stereoselective synthesis,
- aldehyde and ketone,
- diazo compound
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