Citation: Xiao Chunxia, Cao Lin, Wang Jia, Miao Yinlong, Fan Huafang. Advances in the Collective Synthesis of Lycopodium Alkaloids[J]. Chinese Journal of Organic Chemistry, ;2017, 37(4): 810-823. doi: 10.6023/cjoc201611032 shu

Advances in the Collective Synthesis of Lycopodium Alkaloids

Xiao Chunxia ^a ,
Cao Lin ^a ,
Wang Jia ^a ,
Miao Yinlong ^a ,
Fan Huafang ^a,b,*,,

a.
Shaanxi Key Laboratory of Natural Products & Chemical Biology, Northwest A & F University, Yangling 712100
b.
Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032

Corresponding author: Fan Huafang, fhf@nwafu.edu.cn
Received Date: 24 November 2016
Revised Date: 24 December 2016

Fund Project: the National Natural Science Foundation of China 21403169the Postdoctoral Science Foundation of China 2013M532084the Chinese Universities Scientific Fund 2452015079the National Natural Science Foundation of China 21502153

Figures(17)

In view of the relevance between chemical structures and biosynthetic pathways of compounds that belong to the same family of natural products, MacMillan et al. (2011) proposed a strategy for the rapid and efficient synthesis of natural product within a family from a common intermediate or a group of similar intermediates, which is termed as collective synthesis. In recent years, this strategy has been applied for the synthesis of multiple family of natural products. Lycopodium alkaloids are a class of structurally diverse alkaloids, and many of them exhibiting good biological activity. In this review, the progress in the collective synthesis of Lycopodium alkaloids is summarized.
- Lycopodium alkaloids,
- natural products,
- total synthesis,
- collective synthesis
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