Citation: Tan Fen, Xiao Wenjing, Zeng Guoping. Recent Advances in 3-Isothiocyanato Oxindoles Engaged Asymmetric Cascade Reactions[J]. Chinese Journal of Organic Chemistry, ;2017, 37(4): 824-840. doi: 10.6023/cjoc201611017 shu

Recent Advances in 3-Isothiocyanato Oxindoles Engaged Asymmetric Cascade Reactions

Tan Fen ^a,b,*,, ,
Xiao Wenjing ^b ,
Zeng Guoping ^a

a.
Hubei Key Laboratory of Purification and Application of Plant Anti-cancer Active Ingredients, Hubei University of Education, Wuhan 430205
b.
Key Laboratory of Pesticide & Chemical Biology Ministry of Education and College of Chemistry, Central China Normal University, Wuhan 430079

Corresponding author: Tan Fen, tanfen@hue.edu.cn
Received Date: 15 November 2016
Revised Date: 21 December 2016

Fund Project: the National Natural Science Foundation of China 21602052the Scientific Research Project of Hubei Provincial Department of Education Q20163004

Figures(17)

3-Isothiocyanato oxindoles have been widely employed as a class of highly reactive and novel reagents in the enantioselective synthesis of diverse spirooxindoles. This review summarizes the recent advances of 3-isothiocyanato oxindoles mediated some types of cascade process in the past six years, including properties of reaction, activation models and synthetic applications. Furthermore, the prospects of this concept are also discussed.
- 3-isothiocyanato oxindole,
- spirooxindole,
- asymmetric synthesis,
- cascade reaction
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