Citation: Fan Weiyong, Yu Lei, Peng Xiangjun, Liu Liangxian. In the Presence of FeCl₃ Reaction of Alknols with Iodine: A Convenient Synthetic Route to Iodocyclic Ethers[J]. Chinese Journal of Organic Chemistry, ;2017, 37(4): 920-924. doi: 10.6023/cjoc201610046 shu

In the Presence of FeCl₃ Reaction of Alknols with Iodine: A Convenient Synthetic Route to Iodocyclic Ethers

Fan Weiyong ^a ,
Yu Lei ^b ,
Peng Xiangjun ^b,*,, ,
Liu Liangxian ^a,*,,

a.
Department of Chemistry and Biology, Gannan Teachers' College, Ganzhou 341000
b.
School of Pharmaceutical Science, Gannan Medical University, Ganzhou 341000

Corresponding author: Peng Xiangjun, pengxiangjun99@126.com Liu Liangxian, lxliu@xmu.edu.cn
Received Date: 31 October 2016
Revised Date: 23 December 2016

Figures(1)

In the presence of FeCl₃ reaction of alkenols with iodine resulted in intramolecular addition of hydroxyl to alkenol to produce a wide range of iodocyclic ethers in good to excellent yields under mild reaction conditions. The advantages of our procedure include a decreased amount of iodine as well as short reaction times. The broad scope, mild reaction conditions, and experimental ease of this transformation have made it a valuable alternative to current available methods for the preparation of iodocyclic ethers.
- intramolecular iodoetherification,
- iron trichloride,
- alkenol
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In the Presence of FeCl3 Reaction of Alknols with Iodine: A Convenient Synthetic Route to Iodocyclic Ethers

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In the Presence of FeCl₃ Reaction of Alknols with Iodine: A Convenient Synthetic Route to Iodocyclic Ethers