Citation: Wang Bing, Li Na, Liu Teng, Wang Ying'ai, Wang Xiaojing, Sun Jie. Research Progress on Synthesis of Nitric Oxide Donor Compounds[J]. Chinese Journal of Organic Chemistry, ;2017, 37(4): 777-797. doi: 10.6023/cjoc201610035 shu

Research Progress on Synthesis of Nitric Oxide Donor Compounds

Wang Bing ^a,b ,
Li Na ^a,b ,
Liu Teng ^a,b ,
Wang Ying'ai ^a,b ,
Wang Xiaojing ^a,b,*,, ,
Sun Jie ^a,b,*,,

a.
School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan 250200
b.
Key Laboratory for Biotech-Drugs Ministry of Health, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062

Corresponding author: Wang Xiaojing, xiaojing6@gmail.com Sun Jie, 635775299@qq.com
Received Date: 21 October 2016
Revised Date: 29 December 2016

Fund Project: the Natural Science Foundation of Shandong Province ZR2015YL041

Figures(39)

Nitric oxide as a biological messenger or effector molecule plays an important physiological role in the body. Owing to its various biological activities, it has received wide attention in clinical practice. Insufficient NO production in vivo is closely related with a variety of diseases. NO donor compounds can release NO in vivo to treat and prevent many diseases. With its wide application in medicine, the methods for the synthesis of NO donor compounds have attracted much attention of researchers. In this paper, the recent advances in the past 10 years in synthetic methods for NO donor compounds are reviewed.
- nitric oxide donor,
- synthetic method,
- pharmacological activity
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沈阳化工大学材料科学与工程学院沈阳 110142