Citation: Dong Hao, Hou Meifang. Recent Progress in Synthesis of Amides[J]. Chinese Journal of Organic Chemistry, ;2017, 37(2): 267-283. doi: 10.6023/cjoc201608014 shu

Recent Progress in Synthesis of Amides

Dong Hao ,
Hou Meifang ^*,,

School of Ecological Technology and Engineering, Shanghai Institute of Technology, Shanghai, 201400

Corresponding author: Hou Meifang, mfhou@sit.edu.cn
Received Date: 21 August 2016
Revised Date: 7 October 2016

Fund Project: the National Natural Science Foundation of China 41171250

Figures(31)

The formation of amide bond is one of the most key reactions in organic chemistry. How to generate amide bond economically is often overlooked as a contemporary challenge as a result of the widespread occurrence of amide polymers, natural products marketed drugs as well as synthetic intermediates. There are inherent drawbacks in the methods. Concerns about their waste and expense are becoming sharper. Thus, Novel chemical protocols to amide formation are being raised. Among a large amount of ways of preparing a amide bond, there has been a growing attention in the use of catalyzed methods for preparing such important functional group. In this review, the catalyst for the formation of an amide bond has become the highlight of some the latest literature in key areas. Alcohols, aldehydes, ketones, unsaturated hydrocarbons, etc., react with organic amines or inorganic amines under a variety of conditions to give the corresponding amide. The review of a new generation of amide-forming reactions may be beneficial to solving these problems.
- amides,
- catalyst,
- organic amine,
- ammonia
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