Citation: Tang Lingjuan, Lu Xinmou, Ji Shunjun. Base Promoted Annulation of Carbodiimides to Access of Quinazoline and Their Derivatives[J]. Chinese Journal of Organic Chemistry, ;2017, 37(3): 746-752. doi: 10.6023/cjoc201607010 shu

Base Promoted Annulation of Carbodiimides to Access of Quinazoline and Their Derivatives

Tang Lingjuan ^a,b ,
Lu Xinmou ^b ,
Ji Shunjun ^b,*,,

a.
Analysis and Testing Center, Nantong University, Suzhou 226019
b.
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123

Corresponding author: Ji Shunjun, shunjun@suda.edu.cn
Received Date: 5 July 2016
Revised Date: 19 October 2016

Figures(6)

An efficient methodology to access of quinazoline derivatives by the reaction of carbodiimides and alcohol under basic conditions has been developed. This paper provides an attractive strategy for construction of the quinazoline compounds and other heterocyclic compounds in a high reaction yield by using simple starting materials in mild reaction conditions and short reaction time.
- carbodiimides,
- α, β-unsaturated ketone,
- quinazoline and their derivatives,
- metal-free
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