Citation: Shi Bochao, Fang Yewen, Zhang Li, Jin Xiaoping, Wu Yonghui, Fang Mei, Yang Yufei, Chen Chong. Advances in the Synthesis of α-Aryl Vinylphosphonates[J]. Chinese Journal of Organic Chemistry, ;2016, 36(4): 673-686. doi: 10.6023/cjoc201601023 shu

Advances in the Synthesis of α-Aryl Vinylphosphonates

Shi Bochao ^a ,
Fang Yewen ^a,, ,
Zhang Li ^c ,
Jin Xiaoping ^b,, ,
Wu Yonghui ^a ,
Fang Mei ^a ,
Yang Yufei ^a ,
Chen Chong ^a

a.
a. School of Chemical Engineering, Ningbo University of Technology, Ningbo 315016;
b.
b. Department of Biology and Pharmaceutical Sciences, Zhejiang Pharmaceutical College, Ningbo 315100;
c.
c. College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan 030024

Corresponding author: Fang Yewen, Jin Xiaoping,
Received Date: 18 January 2016
Available Online: 29 February 2016
Fund Project: 国家自然科学基金(No.21202090) (No.21202090)浙江省自然科学基金(No.LQ13B010004) (No.LQ13B010004)国家大学生创新创业训练计划(No.201411058005) (No.201411058005)新苗人才计划(No.2015R424004) (No.2015R424004)宁波市科技创新团队(No.2011B82002)资助项目. (No.2011B82002)

α-Aryl vinylphosphonates are an important class of organophosphorus compounds and synthetic intermediates for other organophosphorus molecules. The progress of transition-metal-catalyzed synthesis of α-aryl vinylphosphonates including hydrophosphorylation reactions, C-C cross-coupling reactions and C-P cross-coupling reactions is reviewed. The synthetic methods under metal-free conditions are also summarized. The organic transformations of α-aryl vinylphosphonates and their applications in the synthesis of fosmidomycin analogues are also highlighted.
- α-aryl vinylphosphonates,
- arylation,
- hydrophosphorylation,
- cross-coupling reaction
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