Citation: Hu Xiaoyan, Hu Fangzhi, Zhang Minmin, Liao Yijun, Xu Xiaoying, Yuan Weicheng, Zhang Xiaomei. Enantioselective Hydrosilylation of N-Aryl Diaryl Ketimines[J]. Chinese Journal of Organic Chemistry, ;2016, 36(8): 1895-1906. doi: 10.6023/cjoc201512049 shu

Enantioselective Hydrosilylation of N-Aryl Diaryl Ketimines

Hu Xiaoyan ^a,b ,
Hu Fangzhi ^a,b ,
Zhang Minmin ^a,b ,
Liao Yijun ^a,b ,
Xu Xiaoying ^a ,
Yuan Weicheng ^a ,
Zhang Xiaomei ^a,*,,

a.
Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041
b.
University of Chinese Academy of Sciences, Beijing, 100049

Corresponding author: Zhang Xiaomei, xmzhang@cioc.ac.cn
Received Date: 30 December 2015
Revised Date: 2 April 2016

Fund Project: Project supported by the National Natural Science Foundation of China No. 21172217

Figures(1)

Lewis base catalyzed enantioselective hydrosilylation of non-ortho-substituted N-aryl diaryl ketimines was realized. In the presence of 20 mol% of the optimal catalyst, the reactions provided a series of (diarylmethyl)amines with high yields (up to 97%) in moderate to good enantioselectivities (up to 89% ee). The absolute configuration of one product was determined by X-ray crystallographic analysis.
- diarylmethylamines,
- diaryl ketimines,
- chiral Lewis base,
- hydrosilylation
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