Citation: Liu Yuting, Wu Qianqian, Yin Dawei, Li Diyang. Latest Progress and Application of Mannich Reaction[J]. Chinese Journal of Organic Chemistry, ;2016, 36(5): 927-938. doi: 10.6023/cjoc201511024 shu

Latest Progress and Application of Mannich Reaction

1.
Key Laboratory of Auxiliary Chemistry & Technology for Chemical Industry, Ministry of Education, College of Chemistry and Chemical Engineering, Shaanxi University of Science & Technology, Xi'an 710021

Corresponding author: Liu Yuting, lyt@sust.edu.cn
Received Date: 13 November 2015
Revised Date: 15 December 2015

Fund Project: and the Preliminary Projects of National Basic Research Program of China (973 Program) No. 2014CB260411Project supported by the Key Laboratory Project of Shaanxi Provincial Department of Education No. 13J017

Figures(18)

Mannich reaction is very important in organic chemistry, especially plays a very important role in the synthesis of drugs. In addition, Mannich base has widespread attention because of it is more significant and specific biological activity. Mannich reaction, diastereoselectivity Mannich reaction, enantioselective Mannich reaction and the application of Mannich reaction are introduced. Finally, the development aspect of this research is brought forward.
- Mannich reaction,
- Mannich base,
- catalyst,
- application,
- diastereoselectivity,
- enantioselective
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