Citation: Ma Hongli, Yan Xiaojing, Xiao Yumei, Yuan Dekai, Zhang Zhenhua, Fu Bin, Yuan Huizhu. Synthesis and Fungicidal Activities of Azaindolyl Thiazoline Compounds[J]. Chinese Journal of Organic Chemistry, ;2015, 36(1): 158-164. doi: 10.6023/cjoc201507009 shu

Synthesis and Fungicidal Activities of Azaindolyl Thiazoline Compounds

Ma Hongli ^a ,
Yan Xiaojing ^b ,
Xiao Yumei ^a ,
Yuan Dekai ^a ,
Zhang Zhenhua ^a ,
Fu Bin ^a,*,, ,
Yuan Huizhu ^b

a.
Department of Applied Chemistry, China Agricultural University, Beijing 100193
b.
Institute of Plant Protection, Chinese Academy of Agricultural Science, Beijing 100193

Corresponding author: Fu Bin, fubinchem@cau.edu.cn
Received Date: 12 July 2015
Revised Date: 19 August 2015

Fund Project: the National Natural Science Foundation of China 21172255Project supported by the National S & T Pillar Program of China 2011BAE06B02

Figures(1)

In order to find new agrochemical products with high activities, 20 azaindolyl thiazoline compounds were designed and synthesized, and their structures were identified by spectral methods. At the concentration of 50 mg/L, some of the title compounds showed good fungicidal activities. Among those compounds, the EC₅₀ values of 2a and 2d against Phomopsis asparagi and Pyricularia oryzae Cav are 6.55 and 9.66 mg/L, which are superior or comparable to the control pesticides, then they can serve as the lead compounds for new fungicide discovery.
- azaindolyl,
- thiazoline,
- synthesis,
- fungicidal activity
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