Citation:
	            
		            SONG Xue-Jiao,  LIU Zhuang. Applications of Nanotechnology for Physical Stimulus-Responsive Cancer Therapies[J]. Acta Physico-Chimica Sinica,
							;2018, 34(2): 123-139.
						
							doi:
								10.3866/PKU.WHXB201707042
						
					
				
					
				
	        
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	                	Multifunctional theranostic agents that are responsive to external physical stimuli such as light,magnetic field,ultrasound,radiofrequency,and X-rays have been widely explored for their use in physical stimulus-responsive therapies for cancer.Encouraging results in many preclinical animal experiments have been obtained;thus,this innovative strategy has gained great attention.Owing to the nontoxicity of physical stimulus-responsive agents and treatment specificity under particular external stimuli,physical stimulus-responsive cancer therapies provide greatly reduced toxicity and enhanced therapeutic efficiency compared with conventional chemotherapeutic agents.When combining physical stimulus-responsive therapies with other traditional therapeutics,synergistic antitumor effects via various mechanisms can be achieved.In this review,we will summarize the recent developments in physical stimulus-responsive therapies and discuss the important roles of nanoscale theranostic agents in these novel treatment modalities.
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