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Citation: Li Wei-Hua, Lü Guo-Wei, Huang Lan, Gao Hong, Du Wei-Min. Aspirin Synthesis On-line Measurement by Raman Spectroscopy[J]. Acta Physico-Chimica Sinica, ;2003, 19(02): 105-108. doi: 10.3866/PKU.WHXB20030203 shu

Aspirin Synthesis On-line Measurement by Raman Spectroscopy

1.
School of Physics, College of Chemistry and Molecular Engineering, Continue Education School, Peking University, Beijing　100871

Received Date: 5 April 2002
Available Online: 15 February 2003

In this paper, the process of aspirin synthesis was studied by using on-line Raman spectroscopy. Wavelet analysis has been applied to remove the fluorescent background from the Raman spectra, and the variation of components concentration was determined with Multi-wavelength Linear Regression Method. The on-line Raman spectroscopy provided direct information about the variation of components concentration on the reaction time in the synthesis process.
- Raman spectroscopy;Multi-wavelength Linear Regression(MLR) method;　Wavelet analysis;Aspirin;On-line measurement
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