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Citation: Liu Yi, Tan An-Min, Xie Chang-Li, Wang Cun-Xin, Qu Song-Sheng, Hao Zong-Yu. Cell Kinetic Study II.Thermokinetic Study of the Process of Cell Growth Inhibited by Metabolites[J]. Acta Physico-Chimica Sinica, ;1996, 12(04): 377-381. doi: 10.3866/PKU.WHXB19960419 shu

Cell Kinetic Study II.Thermokinetic Study of the Process of Cell Growth Inhibited by Metabolites

1.
Department of Chemistry,Wuhan University,Wuhan 430072

Received Date: 9 August 1995
Available Online: 15 April 1996

By using an LKB2277 Bioactivity Monitor, we have determined the thermogenesis power curves of four kinds of Brucellas S2(55007), M5 (55009),83-202,83-980. And established the thermokinetic equation for the process of cell growth inhibited by the products of metabolism, as:
Ln[1/(β﹒Pt)-1]=ln[1/(β﹒P0)-1]-k0﹒t
From this equation, the rate constants of cell growth k [= k0(1 - β﹒P0)] were obtained. This thermokinetic equation is very suitable for cell growth of separated culture and is very important for the study of bacterial limited growth and their characteristics.
- Bacterial growth,
- Microcalorimetry,
- Thermokinetics,
- Thermochemistry
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