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Citation: YU Wenhao, QI Yanxia, JIN Yan. Investigation of human milk proteins by proteomics[J]. Chinese Journal of Chromatography, ;2019, 37(5): 471-476. doi: 10.3724/SP.J.1123.2018.12019 shu

Investigation of human milk proteins by proteomics

YU Wenhao ^1,2, ,
QI Yanxia ¹ ,
JIN Yan ²

1.
College of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China;
2.
CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical and Physics, Chinese Academy of Sciences, Dalian 116023, China

Received Date: 12 December 2018

Fund Project: National Key Research and Development Program of China (No. 2018YFC0910302)

Human milk is the optimal food for infant nutrition and growth. Proteins are abundant and represent a key element in human milk. With recent developments in proteomics, more tools are available to explore human milk proteins. This article aims to review the recent investigations of human milk proteins using proteomic methodologies. This review focuses on using proteomics as a tool to study the components of human milk proteins; dynamics of human milk proteins during lactation; comparison of proteome from human milk and other source milk, phosphoprotein and glycoprotein analysis of human milk; endogenous peptides in human milk; and the human milk proteome and its correlation to curing of various diseases. Proteomics technology has enabled the study of human milk proteins in the era of micronutrient research, and the results of these studies will be helpful for further analysis of mother and infant health.
- human milk,
- proteomics,
- protein,
- peptide,
- review
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