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Citation: YAN Lijuan, XU Dunming, XUE Xiaofeng, LIN Liyi, LAI Kang, WANG Jianwen, ZHANG Zhigang. Authenticity identification of manuka honey using liquid chromatography-high resolution mass spectrometry based metabolomic technique[J]. Chinese Journal of Chromatography, ;2019, 37(6): 589-596. doi: 10.3724/SP.J.1123.2018.12011 shu

Authenticity identification of manuka honey using liquid chromatography-high resolution mass spectrometry based metabolomic technique

1.
Inspection and Quarantine Technology Center, Xiamen Customs, Xiamen 361026, China;
2.
Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China;
3.
Sichuan Province Apiculture Management Station, Chengdu 610042, China

Received Date: 6 December 2018

Fund Project: National Key Research and Development Program of China (No. 2017YFC1601600)

A liquid chromatography-high resolution mass spectrometry (LC-HRMS) based metabolomic approach for the discrimination of manuka honey from the domestic honey was developed. The results of multivariate data analysis showed significant discrimination of manuka honey from domestic honey. Furthermore, a partial least squares discrimination model was established for honey discrimination, enabling the correct identification of unknown testing samples. A total of 34 highly expressed metabolic markers were obtained from the developed discrimination model, including 3-phenyllactic acid and 4-hydroxybenzoic acid which had both been previously identified as manuka honey markers. The area under the curve of the constructed marker combination reached 0.99. The developed metabolomic approach provides a new method for the quality control of manuka honey.
- liquid chromatography (LC),
- high resolution mass spectrometry (HRMS),
- metabolomics,
- manuka honey
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