Citation:
ZHANG Jiajie, MENG Zihui, XUE Min, WEI Tianye. Advances in nicotine pretreatment and determination method[J]. Chinese Journal of Chromatography,
;2018, 36(11): 1081-1087.
doi:
10.3724/SP.J.1123.2018.07006
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Nicotine is an important indicator in the quality evaluation of tobacco and its related products. Moreover, it is essential to monitor nicotine presence in the environment, food, and human organs. Therefore, the development of a suitable and efficient determination method is crucial to precisely detect nicotine in various samples and complicated matrices. This article reviews the methods of sample preparation (molecular imprinting technology and solid phase/liquid phase microextraction) and methods for nicotine analysis, such as spectrophotometry, liquid chromatography, gas chromatography, capillary electrophoresis, and electrochemical methods, reported in recent years. The advancement in the applications and scopes of these methods are discussed. Furthermore, the sensitivity, accuracy, and detection efficiency of these methods are elaborated on the basis of the reported nicotine determination methods.
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Keywords:
- nicotine,
- pretreatment,
- detection methods,
- review
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