Citation: SHI Meng, SONG Zhihua, GENG Xuhui, WU Dapeng, GUAN Yafeng. Latest developments of single cell analysis[J]. Chinese Journal of Chromatography, ;2017, 35(1): 105-109. doi: 10.3724/SP.J.1123.2016.08039 shu

Latest developments of single cell analysis

SHI Meng ^1,2, ,
SONG Zhihua ^1,2 ,
GENG Xuhui ¹ ,
WU Dapeng ¹ ,
GUAN Yafeng ¹

1.
Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China;
2.
University of Chinese Academy of Sciences, Beijing 100049, China

Received Date: 31 August 2016

Fund Project: National Natural Science Foundation of China (No. 21405157)

Single cell analysis can reveal the cellular components and physiological behavior diversity. It is on the cutting-edge of bio-analytical chemistry. Challenges on detection limit, resolution, and precise manipulation of cells are really tougher than ever before. This review includes the developments of several main techniques about separation, detection and imaging. At last, the future developments in separation and detection are discussed.
- single-cell,
- separation,
- detection,
- imaging,
- review
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
22. [22]
23. [23]
24. [24]
25. [25]
26. [26]
27. [27]
28. [28]
29. [29]
30. [30]
31. [31]
32. [32]
33. [33]
34. [34]
35. [35]
36. [36]
37. [37]
38. [38]
39. [39]
40. [40]
41. [41]
42. [42]
43. [43]
44. [44]
45. [45]
46. [46]
47. [47]
48. [48]
49. [49]
50. [50]
1. [1]
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