Citation: HUO Juyuan, OUYANG Gangfeng, CHEN Liqiong, WANG Xin. Determination of migratory organotin compounds in toys by headspace-solid phase microextraction coupled with gas chromatography-mass spectrometry[J]. Chinese Journal of Chromatography, ;2016, 34(6): 615-620. doi: 10.3724/SP.J.1123.2016.03015 shu

Determination of migratory organotin compounds in toys by headspace-solid phase microextraction coupled with gas chromatography-mass spectrometry

HUO Juyuan ^1,2 ,
OUYANG Gangfeng ^2,*,, ,
CHEN Liqiong ¹ ,
WANG Xin ¹

1.
Shenzhen Academy of Metrology and Quality Inspection, Shenzhen 518109, China
2.
School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China

Corresponding author: OUYANG Gangfeng, cesoygf@mail.sysu.edu.cn
Received Date: 10 March 2016

Fund Project: Scientific Research Fund of Shenzhen Academy of Metrology and Quality Inspection No. 2015-YN12

A method for the determination of ten migratory organotin compounds in toys was developed using headspace-solid phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS). Toy materials were soaked in 0.07 mol/L HCl for 2 h, then the pH of the soak solution was adjusted to 4.7 by HAc-NaAc buffer. After ethylized with sodium tetraethylborate (NaBEt₄), the soaked solution was agitated and the headspace solid phase microextraction was performed with a 100 μ m polydimethylsiloxane (PDMS) fiber. After extraction, the SPME fiber was directly injected into the GC inlet, and the organotin compounds were separated on a DB-5 capillary column. The limits of detection for the ten organotin compounds were in the range of 0.5-5 μg/kg. The recoveries were in the ranges of 80.7%-118.7% and 86.2%-120.5% at the spiked levels of 0.500 μg/L and 5.00 μg/L. The relation standard deviations (RSDs) were all less than 15%. This method has been used to determine migratory organotin in accessible parts of toys, including coating, plastic, wood and textile. The method is simple, fast, sensitive and solvent-free.
- headspace-solid phase microextraction (HS-SPME),
- gas chromatography-mass spectrometry (GC-MS),
- organotin compounds,
- toys
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