Citation: Vanik GHOULIPOUR, Zahra HASSANKHANI-MAJD. Selective separation and determination of isoproterenol on thin layers of bismuth silicate ion-exchanger[J]. Chinese Journal of Chromatography, ;2015, 33(6): 667-671. doi: 10.3724/SP.J.1123.2015.01014 shu

Selective separation and determination of isoproterenol on thin layers of bismuth silicate ion-exchanger

Vanik GHOULIPOUR ^, ,
Zahra HASSANKHANI-MAJD

1.
Faculty of Chemistry, Kharazmi University, Tehran 15719-14911, Iran

Corresponding author: Vanik GHOULIPOUR,
Received Date: 14 January 2015

A simple and sensitive method for the separation and determination of isoproterenol from other doping drugs has been developed on thin layers of bismuth silicate, a synthetic inorganic ion exchanger as adsorbent in thin layer chromatography (TLC). A mixture of methanol and 0.1 mol/L formic acid (3:7, v/v) was employed as the mobile phase. The development time was 32 min. The quantitative measurement were performed with a Camag TLC Scanner-3 at wavelength (λ) of 410 nm. The isoproterenol recovery in this procedure was 98.9%. The linear correlation coefficient was greater than 0.9871 and the relative standard deviation (RSD) was less than 0.94. The limit of detection (LOD) and limit of quantification (LOQ) were 7.7×10^-7mol/L and 3.85 ×10^-6mol/L, respectively. This method has been applied in the determination of isoproterenol in dosage forms and in biological fluids.
- high performance thin layer chromatography (HPTLC),
- inorganic ion-exchanger,
- densitometry
1. [1]
  [1] Conway L, Morgan D. Drugs in Sports. London: British Medical Association, 2002
2. [2]
  [2] Jimnez C, Ventura R, Segura J. J Chromatogr B, 2002, 767: 341
3. [3]
  [3] Mueller R K, Grosse J, Lang R, et al. J Chromatogr B, 1995, 674: 1
4. [4]
  [4] Sherma J, Fried B. Handbook of Thin-Layer Chromatography. New York: Marcel Dekker Inc., 1991: 407
5. [5]
  [5] Sherma J. Anal Chem, 2010, 82: 4895
6. [6]
  [6] Qureshi M, Varshney K G. Inorganic Ion-Exchangers in Chemical Analysis. Florida: CRC Press, 1991
7. [7]
  [7] Husain S W, Ghoulipour V, Sepahrian H. Acta Chromatogr, 2004, 14: 102
8. [8]
  [8] Bowers L D, Podraza J. USADA Guide to Prohibited Classes of Substances and Prohibited Methods of Doping. Colorado: Anti-Doping Agency, 2002: 7
9. [9]
  [9] Shaw P A, Yu W A. Life Sci, 2001, 70: 301
10. [10]
  [10] Nieto J L, Laviada I D, Guillen A, et al. Cell Signal, 1993, 5: 169
11. [11]
  [11] Krenek P, Kmecova J, Kucerova D, et al. Eur J Heart Fail, 2009, 11(12): 140
12. [12]
  [12] Watson J R, Lawrence R C. J Pharm Sci, 1977, 66: 560
13. [13]
  [13] Liu Y M, Cao J T, Zheng Y L, et al. J Sep Sci, 2008, 31(13): 2463
14. [14]
  [14] Zhou G J, Zhang G F, Chen H Y. Anal Chem Acta, 2002, 463: 257
15. [15]
  [15] Zhang C, Huang J, Zhang Z, et al. Anal Chem Acta, 1998, 374: 105
16. [16]
  [16] Al-Warthan A A, Al-Tamrah S A, Al-Akel A. Anal Sci, 1994, 10: 449
17. [17]
  [17] Bonifacio Y G, Marccoline-Junior L H, Fatibello-Filho O. Anal Lett, 2004, 37(10): 2111
18. [18]
  [18] Lupetti K O, Vieira I C, Fatibello-Filho O. Talanta, 2002, 57: 135
19. [19]
  [19] Solieh P, Polydorou C K, Koupparis M A, et al. J Pharm Biomed Anal, 2000, 22: 781
20. [20]
  [20] Nevado J J B, Gallego J M L, Laguna P B. Anal Chem Acta, 1995, 300: 293
21. [21]
  [21] Ensafi A A, Khoddami E, Karimi-Maleh H. Int J Electrochem Sci, 2011, 6: 2596
22. [22]
  [22] Kutluay A, Aslanoglu M. Acta Chim Slov, 2010, 57: 157
23. [23]
  [23] Elord J L, Schmit J L, Morley J A. J Chromatogr A, 1996, 723: 235
24. [24]
  [24] Hassankhani-Majd Z, Ghoulipour V, Husain S W. Acta Chromatogr, 2006, 16: 173
25. [25]
  [25] Ahuja S, Scypinski S. Handbook of Modern Pharmaceutical Analysis. Burlington: Academic Press, 2011: 430
26. [26]
  [26] Ghoulipour V, Husain S W. Anal Sci, 2000, 16: 1079
27. [27]
  [27] ICH Guidelines Q2B, Validation of Analytical Procedures: Methodology (CPMP/ICH/281/95). Geneva, 1996
28. [28]
  [28] Papp E, Farkas A, Otta K H, et al. J Planar Chromatogr, 2000, 13: 328
29. [29]
  [29] Ferenczi-Fodor K, Vegh Z, Nagy-Turak A, et al. J AOAC Int, 2001, 84: 1265
30. [30]
  [30] Dallas F A A, Read H, Ruane R J, et al. Recent Advances in Thin-Layer Chromatography. New York: Springer, 1988: 11
31. [31]
  [31] Ferenczi-Fodor K, Renger B, Vegh Z. J Planar Chromatogr, 2010, 23: 173
32. [32]
  [32] Ramirez A, Gutierrez R, Diaz G, et al. J Chromatogr B, 2003, 784: 315
33. [33]
  [33] Mazlom-Ardakani M, Sabaghian F, Khoshroo A, et al. Chin J Catal, 2014, 35: 565
34. [34]
  [34] Lupetti K O, Vieira I C, Fatibello-Filho O. Talanta, 2002, 57: 135
35. [35]
  [35] Rezaei B, Ensafi A A, Haghighatnia F. Anal Methods, 2012, 4: 1753
36. [36]
  [36] Rocha F R P, Nobrega J A, Fatibello D. Green Chem, 2001, 3: 216
1. [1]
  Jiayu Bai , Songjie Hu , Lirong Feng , Xinhui Jin , Dong Wang , Kai Zhang , Xiaohui Guo . Manganese vanadium oxide composite as a cathode for high-performance aqueous zinc-ion batteries. Chinese Chemical Letters, 2024, 35(9): 109326-. doi: 10.1016/j.cclet.2023.109326
2. [2]
  Ningning Zhao , Yuyan Liang , Wenjie Huo , Xinyan Zhu , Zhangxing He , Zekun Zhang , Youtuo Zhang , Xianwen Wu , Lei Dai , Jing Zhu , Ling Wang , Qiaobao Zhang . Separator functionalization enables high-performance zinc anode via ion-migration regulation and interfacial engineering. Chinese Chemical Letters, 2024, 35(9): 109332-. doi: 10.1016/j.cclet.2023.109332
3. [3]
  Wenli Xu , Yingzhao Zhang , Rui Wang , Chenyang Liu , Jialin Liu , Xiangyu Huo , Xinying Liu , He Zhang , Jianxu Ding . In-situ passivating surface defects of ultra-thin MAPbBr3 perovskite single crystal films for high performance photodetectors. Chinese Journal of Structural Chemistry, 2025, 44(1): 100454-100454. doi: 10.1016/j.cjsc.2024.100454
4. [4]
  Mei-Chen Liu , Qing-Song Liu , Yi-Zhou Quan , Jia-Ling Yu , Gang Wu , Xiu-Li Wang , Yu-Zhong Wang . Phosphorus-silicon-integrated electrolyte additive boosts cycling performance and safety of high-voltage lithium-ion batteries. Chinese Chemical Letters, 2024, 35(8): 109123-. doi: 10.1016/j.cclet.2023.109123
5. [5]
  Ya Song , Mingxia Zhou , Zhu Chen , Huali Nie , Jiao-Jing Shao , Guangmin Zhou . Integrated interconnected porous and lamellar structures realized fast ion/electron conductivity in high-performance lithium-sulfur batteries. Chinese Chemical Letters, 2024, 35(6): 109200-. doi: 10.1016/j.cclet.2023.109200
6. [6]
  Zhong-Hui Sun , Yu-Qi Zhang , Zhen-Yi Gu , Dong-Yang Qu , Hong-Yu Guan , Xing-Long Wu . CoPSe nanoparticles confined in nitrogen-doped dual carbon network towards high-performance lithium/potassium ion batteries. Chinese Chemical Letters, 2025, 36(1): 109590-. doi: 10.1016/j.cclet.2024.109590
7. [7]
  Ruofan Yin , Zhaoxin Guo , Rui Liu , Xian-Sen Tao . Ultrafast synthesis of Na₃V₂(PO₄)₃ cathode for high performance sodium-ion batteries. Chinese Chemical Letters, 2025, 36(2): 109643-. doi: 10.1016/j.cclet.2024.109643
8. [8]
  Huanyan Liu , Jiajun Long , Hua Yu , Shichao Zhang , Wenbo Liu . Rational design of highly conductive and stable 3D flexible composite current collector for high performance lithium-ion battery electrodes. Chinese Chemical Letters, 2025, 36(3): 109712-. doi: 10.1016/j.cclet.2024.109712
9. [9]
  Shuo Zhang , Haitao Liao , Zhi-Qun Liu , Chong Yan , Jia-Qi Huang . Re-evaluating the nano-sized inorganic protective layer on Cu current collector for anode free lithium metal batteries. Chinese Chemical Letters, 2024, 35(7): 109284-. doi: 10.1016/j.cclet.2023.109284
10. [10]
  Hui Liu , Xiangyang Tang , Zhuang Cheng , Yin Hu , Yan Yan , Yangze Xu , Zihan Su , Futong Liu , Ping Lu . Constructing multifunctional deep-blue emitters with weak charge transfer excited state for high-performance non-doped blue OLEDs and single-emissive-layer hybrid white OLEDs. Chinese Chemical Letters, 2024, 35(10): 109809-. doi: 10.1016/j.cclet.2024.109809
11. [11]
  Ting Shi , Ziyang Song , Yaokang Lv , Dazhang Zhu , Ling Miao , Lihua Gan , Mingxian Liu . Hierarchical porous carbon guided by constructing organic-inorganic interpenetrating polymer networks to facilitate performance of zinc hybrid supercapacitors. Chinese Chemical Letters, 2025, 36(1): 109559-. doi: 10.1016/j.cclet.2024.109559
12. [12]
  Xinpin Pan , Yongjian Cui , Zhe Wang , Bowen Li , Hailong Wang , Jian Hao , Feng Li , Jing Li . Robust chemo-mechanical stability of additives-free SiO₂ anode realized by honeycomb nanolattice for high performance Li-ion batteries. Chinese Chemical Letters, 2024, 35(10): 109567-. doi: 10.1016/j.cclet.2024.109567
13. [13]
  Hengyi ZHU , Liyun JU , Haoyue ZHANG , Jiaxin DU , Yutong XIE , Li SONG , Yachao JIN , Mingdao ZHANG . Efficient regeneration of waste LiNi_0.5Co_0.2Mn_0.3O₂ cathode toward high-performance Li-ion battery. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 625-638. doi: 10.11862/CJIC.20240358
14. [14]
  Pu Zhang , Xiang Mao , Xuehua Dong , Ling Huang , Liling Cao , Daojiang Gao , Guohong Zou . Two UV organic-inorganic hybrid antimony-based materials with superior optical performance derived from cation-anion synergetic interactions. Chinese Chemical Letters, 2024, 35(9): 109235-. doi: 10.1016/j.cclet.2023.109235
15. [15]
  Yuhuan Meng , Long Zhang , Lequan Wang , Junming Kang , Hongbin Lu . 20 nm-ultra-thin fluorosiloxane interphase layer enables dendrite-free, fast-charging, and flexible aqueous zinc metal batteries. Chinese Chemical Letters, 2024, 35(12): 110025-. doi: 10.1016/j.cclet.2024.110025
16. [16]
  Yang Li , Xiaoxu Liu , Tianyi Ji , Man Zhang , Xueru Yan , Mengjie Yao , Dawei Sheng , Shaodong Li , Peipei Ren , Zexiang Shen . Potassium ion doped manganese oxide nanoscrolls enhanced the performance of aqueous zinc-ion batteries. Chinese Chemical Letters, 2025, 36(1): 109551-. doi: 10.1016/j.cclet.2024.109551
17. [17]
  Kexin Yuan , Yulei Liu , Haoran Feng , Yi Liu , Jun Cheng , Beiyang Luo , Qinglian Wu , Xinyu Zhang , Ying Wang , Xian Bao , Wanqian Guo , Jun Ma . Unlocking the potential of thin-film composite reverse osmosis membrane performance: Insights from mass transfer modeling. Chinese Chemical Letters, 2024, 35(5): 109022-. doi: 10.1016/j.cclet.2023.109022
18. [18]
  Weihong Ding , Kaiyue Song , Xianglong Li , Xiaoxia Sun . High-temperature-stable RRAMs with well-defined thermal effect mechanisms enable by engineering of robust 2D <100>-oriented organic-inorganic hybrid perovskites. Chinese Chemical Letters, 2025, 36(4): 110495-. doi: 10.1016/j.cclet.2024.110495
19. [19]
  Panke Zhou , Hong Yu , Mun Yin Chee , Tao Zeng , Tianli Jin , Hongling Yu , Shuo Wu , Wen Siang Lew , Xiong Chen . Electron push-pull effects induced performance promotion in covalent organic polymer thin films-based memristor for neuromorphic application. Chinese Chemical Letters, 2024, 35(5): 109279-. doi: 10.1016/j.cclet.2023.109279
20. [20]
  Hao-Fei Ni , Jia-He Lin , Gele Teri , Qiang-Qiang Jia , Pei-Zhi Huang , Hai-Feng Lu , Chang-Feng Wang , Zhi-Xu Zhang , Da-Wei Fu , Yi Zhang . B-site ion regulation strategy enables performance optimization and multifunctional integration of hybrid perovskite ferroelectrics. Chinese Chemical Letters, 2025, 36(3): 109690-. doi: 10.1016/j.cclet.2024.109690

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(175)
HTML views(27)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142