Citation: CAO Xinyue, PANG Guofang, JIN Linghe, KANG Jian, HU Xueyan, CHANG Qiaoying, WANG Minglin, FAN Chunlin. Comparison of the performances of gas chromatography- quadrupole time of flight mass spectrometry and gas chromatography-tandem mass spectrometry in rapid screening and confirmation of 208 pesticide residues in fruits and vegetables[J]. Chinese Journal of Chromatography, ;2015, 33(4): 389-396. doi: 10.3724/SP.J.1123.2014.12026 shu

Comparison of the performances of gas chromatography- quadrupole time of flight mass spectrometry and gas chromatography-tandem mass spectrometry in rapid screening and confirmation of 208 pesticide residues in fruits and vegetables

CAO Xinyue ^1,2 ,
PANG Guofang ² ,
JIN Linghe ^1,2 ,
KANG Jian ^2,3 ,
HU Xueyan ² ,
CHANG Qiaoying ^2,3 ,
WANG Minglin ^1,, ,
FAN Chunlin ^2,,

1.
1. College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, China;

Corresponding author: WANG Minglin, FAN Chunlin,
Received Date: 18 December 2014
Available Online: 19 January 2015
Fund Project: "十二五"国家科技支撑项目(2012BAD29B01). (2012BAD29B01)

The performances of gas chromatography-tandem mass spectrometry (GC-MS/MS) and gas chromatography quadrupole time of flight mass spectrometry (GC-QTOF/MS) for the determination of 208 pesticide residues in fruit and vegetable samples, including apple, orange, tomato and cucumber, were compared comprehensively. Based on the differences of the two instruments, their respective characteristics and scopes of application in the detection of the pesticide residues were presented, which provided the reference for the analysis of pesticide residues. The performance parameters of the two instruments, such as overall recoveries, precisions, limits of detection, linear ranges, identification points and matrix effects, were evaluated according to a designed experiment. At three spiked levels (5.0, 10.0 and 20.0 μg/kg), the average recoveries for the majority of pesticides (93.0%) ranged from 70% to 120% in the four matrices with relative standard deviations below 20%. The limits of detection for most of the pesticides by GC-MS/MS and GC-Q-TOF/MS were less than 5.0 μg/kg. Compared with GC-QTOF/MS, GC-MS/MS showed relatively lower limits of detection and wider linear ranges, and its performance was more satisfactory in accurate quantitative analysis due to its superior sensitivity. On the other hand, GC-QTOF/MS provided accurate mass measurement, which was proved to be an efficient analytical tool on the rapid screening and confirmation of a large number of pesticides and non-target compounds.
1. [1]
  [1] Wang J, Leung D. J Agric Food Chem, 2009, 57(6): 2162
2. [2]
  [2] Codex Alimentarius Commission. Pesticide Residues in Food and Feed (2013). ［2014-09-29］. http://www.codexalimentarius.net/pestres/data/pesticides/search.html?lang=en
3. [3]
  [3] European Commission. Pesticide EU-MRLs. (2014-10-14) ［2014-09-29］. http://ec.europa.eu/sanco_pesticides/public/?event=homepage
4. [4]
  [4] The Japan Food Chemical Research Foundation. Maximum Residue Limits (MRLs) List of Agricultural Chemicals in Foods. (2014-01-30)［2014-09-29］. http://www.m5.ws001.squarestart.ne.jp/foundation/search.html
5. [5]
  [5] GB 2763-2014
6. [6]
  [6] Cao Z Y, Mou R X, Wu L, et al. Chinese Journal of Chromatography (曹赵云, 牟仁祥, 吴俐, 等. 色谱), 2014, 32(12): 1390
7. [7]
  [7] Tian H Z, Zhao Y B, Zhou Y M. Food Science (田宏哲, 赵瑛博, 周艳明. 食品科学), 2011, 32(2): 187
8. [8]
  [8] Liu Y, Tang Y F, Song J F, et al. Chinese Journal of Chromatography (刘永, 唐英斐, 宋金凤, 等. 色谱), 2014, 32(2): 139
9. [9]
  [9] Cheng Z, Zhang R, Liu W H, et al. Chinese Journal of Chromatography (程志, 张蓉, 刘韦华, 等. 色谱), 2014, 32(1): 57
10. [10]
  [10] Chen N, Zhang J H. Criminal Technology (陈宁, 张建华. 刑事技术), 2005(2): 31
11. [11]
  [11] Camino-Sánchez F J, Zafra-Gomez A, Ruiz-García J, et al. J Food Compos Anal, 2011, 24(3): 427
12. [12]
  [12] Ma Z L, Zhao W, Li L Y, et al. Chinese Journal of Chromatography (马智玲, 赵文, 李凌云, 等. 色谱), 2013, 31(3): 228
13. [13]
  [13] Ferrer I, Thurman E M, Fernández-Alba A R. Anal Chem, 2005, 77(9): 2818
14. [14]
  [14] Portolés T, Sancho J V, Hernández F, et al. J Mass Spectrom, 2010, 45(8): 926
15. [15]
  [15] Li X J, Peng T, Li C J. Journal of Instrumental Analysis (李晓娟, 彭涛, 李重九. 分析测试学报), 2012, 31(5): 628
16. [16]
  [16] Hayward D G, Wong J W. Anal Chem, 2009, 81(14): 5716
17. [17]
  [17] Jiang J, Li P W, Xie L H, et al. Chinese Journal of Analytical Chemistry (姜俊, 李培武, 谢立华, 等. 分析化学), 2011, 39(1): 72
18. [18]
  [18] Cervera M I, Portolés T, Pitarch E, et al. J Chromatogr A, 2012, 1244: 168
19. [19]
  [19] Li X Y, Zhang H Y, Chang Q Y, et al. Chinese Journal of Chromatography (李晓颍, 张红医, 常巧英, 等. 色谱), 2014, 32(3): 268
20. [20]
  [20] SANCO 12571-2013
21. [21]
  [21] EC 657-2002
22. [22]
  [22] Kmellár B, Fodor6 P, Pareja L, et al. J Chromatogr A, 2008, 1215(1/2): 37
23. [23]
  [23] Hou X, Yi S G, Han M, et al. Modern Scientific Instruments (侯雪, 易盛国, 韩梅, 等. 现代科学仪器), 2012(4): 115
24. [24]
  [24] Li X Y, Zhang H Y, Fan C L, et al. Chinese Journal of Chemistry (李晓颍, 张红医, 范春林, 等. 化学通报), 2014, 77(2): 123
1. [1]
  Zunxiang Zeng , Yuling Hu , Yufei Hu , Hua Xiao . Analysis of Plant Essential Oils by Supercritical CO₂Extraction with Gas Chromatography-Mass Spectrometry: An Instrumental Analysis Comprehensive Experiment Teaching Reform. University Chemistry, 2024, 39(3): 274-282. doi: 10.3866/PKU.DXHX202309069
2. [2]
  Yanhui Zhong , Ran Wang , Zian Lin . Analysis of Halogenated Quinone Compounds in Environmental Water by Dispersive Solid-Phase Extraction with Liquid Chromatography-Triple Quadrupole Mass Spectrometry. University Chemistry, 2024, 39(11): 296-303. doi: 10.12461/PKU.DXHX202402017
3. [3]
  Xiaowu Zhang , Pai Liu , Qishen Huang , Shufeng Pang , Zhiming Gao , Yunhong Zhang . Acid-Base Dissociation Equilibrium in Multiphase System: Effect of Gas. University Chemistry, 2024, 39(4): 387-394. doi: 10.3866/PKU.DXHX202310021
4. [4]
  Jiao CHEN , Yi LI , Yi XIE , Dandan DIAO , Qiang XIAO . Vapor-phase transport of MFI nanosheets for the fabrication of ultrathin b-axis oriented zeolite membranes. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 507-514. doi: 10.11862/CJIC.20230403
5. [5]
  Shiyu Zhang , Jing Cai , Xinran Hou , Qing Zhou . A Comparative Study on Higher Chemistry Education Curriculum between China and the United Kingdom. University Chemistry, 2024, 39(11): 397-405. doi: 10.12461/PKU.DXHX202401050
6. [6]
  Chongjing Liu , Yujian Xia , Pengjun Zhang , Shiqiang Wei , Dengfeng Cao , Beibei Sheng , Yongheng Chu , Shuangming Chen , Li Song , Xiaosong Liu . Understanding Solid-Gas and Solid-Liquid Interfaces through Near Ambient Pressure X-Ray Photoelectron Spectroscopy. Acta Physico-Chimica Sinica, 2025, 41(2): 100013-. doi: 10.3866/PKU.WHXB202309036
7. [7]
  Qilong Fang , Yiqi Li , Jiangyihui Sheng , Quan Yuan , Jie Tan . Magical Pesticide Residue Detection Test Strips: Aptamer-based Lateral Flow Test Strips for Organophosphorus Pesticide Detection. University Chemistry, 2024, 39(5): 80-89. doi: 10.3866/PKU.DXHX202310004
8. [8]
  Mingyang Men , Jinghua Wu , Gaozhan Liu , Jing Zhang , Nini Zhang , Xiayin Yao . 液相法制备硫化物固体电解质及其在全固态锂电池中的应用. Acta Physico-Chimica Sinica, 2025, 41(1): 2309019-. doi: 10.3866/PKU.WHXB202309019
9. [9]
  Zian Lin , Yingxue Jin . Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) for Disease Marker Screening and Identification: A Comprehensive Experiment Teaching Reform in Instrumental Analysis. University Chemistry, 2024, 39(11): 327-334. doi: 10.12461/PKU.DXHX202403066
10. [10]
  Zhiwen HU , Weixia DONG , Qifu BAO , Ping LI . Low-temperature synthesis of tetragonal BaTiO₃ for piezocatalysis. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 857-866. doi: 10.11862/CJIC.20230462
11. [11]
  Gaoyan Chen , Chaoyue Wang , Juanjuan Gao , Junke Wang , Yingxiao Zong , Kin Shing Chan . Heart to Heart: Exploring Cardiac CT. University Chemistry, 2024, 39(9): 146-150. doi: 10.12461/PKU.DXHX202402011
12. [12]
  Hao Wu , Zhen Liu , Dachang Bai . ¹H NMR Spectrum of Amide Compounds. University Chemistry, 2024, 39(3): 231-238. doi: 10.3866/PKU.DXHX202309020
13. [13]
  Jingming Li , Bowen Ding , Nan Li , Nurgul . Application of Comparative Teaching Method in Experimental Project Design of Instrumental Analysis Course: A Case Study in Chromatography Experiment Teaching. University Chemistry, 2024, 39(8): 263-269. doi: 10.3866/PKU.DXHX202312078
14. [14]
  Haiyang Zhang , Yanzhao Dong , Haojie Li , Ruili Guo , Zhicheng Zhang , Jiangjiexing Wu . Exploring the Integration of Chemical Engineering Principle Experiment with Cutting-Edge Research Achievements. University Chemistry, 2024, 39(10): 308-313. doi: 10.12461/PKU.DXHX202405035
15. [15]
  Fang Niu , Rong Li , Qiaolan Zhang . Analysis of Gas-Solid Adsorption Behavior in Resistive Gas Sensing Process. University Chemistry, 2024, 39(8): 142-148. doi: 10.3866/PKU.DXHX202311102
16. [16]
  Renxiao Liang , Zhe Zhong , Zhangling Jin , Lijuan Shi , Yixia Jia . A Palladium/Chiral Phosphoric Acid Relay Catalysis for the One-Pot Three-Step Synthesis of Chiral Tetrahydroquinoline. University Chemistry, 2024, 39(5): 209-217. doi: 10.3866/PKU.DXHX202311024
17. [17]
  Fan Wu , Wenchang Tian , Jin Liu , Qiuting Zhang , YanHui Zhong , Zian Lin . Core-Shell Structured Covalent Organic Framework-Coated Silica Microspheres as Mixed-Mode Stationary Phase for High Performance Liquid Chromatography. University Chemistry, 2024, 39(11): 319-326. doi: 10.12461/PKU.DXHX202403031
18. [18]
  Jingyu Cai , Xiaoyu Miao , Yulai Zhao , Longqiang Xiao . Exploratory Teaching Experiment Design of FeOOH-RGO Aerogel for Photocatalytic Benzene to Phenol. University Chemistry, 2024, 39(4): 169-177. doi: 10.3866/PKU.DXHX202311028
19. [19]
  Xiaotian ZHU , Fangding HUANG , Wenchang ZHU , Jianqing ZHAO . Layered oxide cathode for sodium-ion batteries: Surface and interface modification and suppressed gas generation effect. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 254-266. doi: 10.11862/CJIC.20240260
20. [20]
  Zhuoming Liang , Ming Chen , Zhiwen Zheng , Kai Chen . Multidimensional Studies on Ketone-Enol Tautomerism of 1,3-Diketones By ¹H NMR. University Chemistry, 2024, 39(7): 361-367. doi: 10.3866/PKU.DXHX202311029

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(394)
HTML views(21)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142