Citation: GAN Wei, LIU Xuemin, SUN Jing. Regression evaluation index intelligent filter method for quick optimization of chromatographic separation conditions[J]. Chinese Journal of Chromatography, ;2015, 33(2): 140-145. doi: 10.3724/SP.J.1123.2014.09040 shu

Regression evaluation index intelligent filter method for quick optimization of chromatographic separation conditions

  • Corresponding author: GAN Wei, 
  • Received Date: 25 September 2014
    Available Online: 10 December 2014

  • This paper presents a method of regression evaluation index intelligent filter method (REIFM) for quick optimization of chromatographic separation conditions. The hierarchical chromatography response function was used as the chromatography-optimization index. The regression model was established by orthogonal regression design. The chromatography-optimization index was filtered by the intelligent filter program, and the optimization of the separation conditions was obtained. The experimental results showed that the average relative deviation between the experimental values and the predicted values was 0.18% at the optimum and the optimization results were satisfactory.
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