Citation: SHAN Yichu, ZHANG Lihua, ZHANG Yukui. Advances and applications of selective reaction monitoring technology in proteomics study[J]. Chinese Journal of Chromatography, ;2014, 32(4): 330-335. doi: 10.3724/SP.J.1123.2013.12019 shu

Advances and applications of selective reaction monitoring technology in proteomics study

1.
Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; National Chromatographic Research and Analysis Center, Dalian 116023, China

Corresponding author: ZHANG Lihua,
Received Date: 18 December 2013
Available Online: 9 January 2014
Fund Project: 国家重大科学计划“蛋白质定量新方法及相关技术研究”项目(2012CB910604). (2012CB910604)

As an important technology for targeted protein analysis, selective reaction monitoring technology (SRM) improves the detection sensitivity and quantification accuracy by eliminating the interference of impurities and co-eluting peptides by selective detection of specific mother ions and daughter ions. It has been widely applied to the quantitative proteomics study due to the advantages of high selectivity, excellent reproducibility, high sensitivity and wide dynamic range and plays an important role in the area of life science. For the quantitative analysis of the complex samples with wide dynamic range, the throughput of analysis and detection sensitivity still need to be improved. Moreover, various quantification strategies have been proposed to improve the accuracy and precision of quantification. Furthermore, data processing becomes more and more important with the application of SRM technology to the analysis of complex samples. In this work, the recent development of SRM technology is reviewed from the above mentioned aspects. Since SRM technology gains wider applications along with the technological development, its applications in the area of proteomics quantitative study including biomarker validation, post-translational proteomics study (phosphorylation, glycosation, acetylation and so on), biotechnology and signaling pathway analysis are briefly described. Finally, the future developments, applications and outlook of SRM technology are described.
- selective reaction monitoring (SRM),
- proteomics,
- quantification,
- review
1. [1]
  [1] Gallien S, Duriez E, Domon B J. Mass Spectrom, 2011, 46(3): 298
2. [2]
  [2] Kiyonami R, Schoen A, Prakash A, et al. Mol Cell Proteomics, 2011, 10(2), DOI: 10.1074/mcp. M110.002931
3. [3]
  [3] Mao X L, Wei J Y, Niu M, et al. Chinese Journal of Chromatography (毛心丽, 卫军营, 牛明, 等. 色谱), 2012, 30(2): 170
4. [4]
  [4] Gillet L C, Navarro P, Tate S, et al. Mol Cell Proteomics, 2012, 11(6), DOI: 10.1074/mcp. O111.016717
5. [5]
  [5] Whiteaker J R, Zhao L, Abbatiello S E, et al. Mol Cell Proteomics, 2011, 10(4), DOI: 10.1074/mcp. M110.005645
6. [6]
  [6] Hossain M, Kaleta D T, Robinson E W, et al. Mol Cell Proteomics, 2011, 10(2), DOI: 10.1074/mcp. M000062-MCP201
7. [7]
  [7] Rafalko A, Dai S J, Hancock W S, et al. J Proteome Res, 2012, 11(2): 808
8. [8]
  [8] Choi S, Kim J, Yea K, et al. Anal Biochem, 2010, 401: 196
9. [9]
  [9] Picotti P, Bodenmiller B, Mueller L N, et al. Cell, 2009, 138: 795
10. [10]
  [10] Jovanovic M, Reiter L, Picotti P, et al. Nat Methods, 2010, 7: 837
11. [11]
  [11] Zhao Y, Jia W, Sun W, et al. J Proteome Res, 2010, 9: 3319
12. [12]
  [12] Zhang H X, Liu Q F, Zimmerman L J, et al. Mol Cell Proteomics, 2011, 10(6), DOI: 10.1074/mcp. M110.006593
13. [13]
  [13] Huillet C, Adrait A, Lebert D, et al. Mol Cell Proteomics, 2012, 11(2), DOI: 10.1074/mcp. M111.008235
14. [14]
  [14] Reiter L, Rinner O, Picotti P, et al. Nat Methods, 2011, 8(5): 430
15. [15]
  [15] Brusniak M Y K, Kwok S T, Christiansen M, et al. BMC Bioinformatics, 2011, 12: 78
16. [16]
  [16] Cham J A, Bianco L, Barton C, et al. J Proteome Res, 2010, 9(1): 620
17. [17]
  [17] Huttenhain R, Surinova S, Ossola R, et al. Mol Cell Proteomics, 2013, 12(4): 1005
18. [18]
  [18] Lehnert S, Jesse S, Rist W, et al. Exp Neurol, 2012, 234(2): 499
19. [19]
  [19] Wang Q, Chaerkady R, Wu J A, et al. P Natl Acad Sci USA, 2011, 108(6): 2444
20. [20]
  [20] Hüttenhain R, Soste M, Selevsek N, et al. Sci Transl Med, 2012, 4(142): 142ra97
21. [21]
  [21] Percy A J, Chambers A G, Yang J, et al. Biochim Biophys Acta, 2013, DOI: 10.1016/j. bbapap.2013.06.008
22. [22]
  [22] Tang H Y, Beer L A, Barnhart K T, et al. J Proteome Res, 2011, 10(9): 4005
23. [23]
  [23] Tang H Y, Beer L A, Chang-Wong T, et al. J Proteome Res, 2012, 11(2): 678
24. [24]
  [24] Thingholm T E, Bak S, Beck-Nielsen H, et al. Mol Cell Proteomics, 2011, 10(9), DOI: 10.1074/mcp. M110. 006650
25. [25]
  [25] IJsselstijn L, Dekker L J, Koudstaal P J, et al. J Proteome Res, 2011, 10(4): 2006
26. [26]
  [26] Thambisetty M, Simmons A, Velayudhan L, et al. Arch Gen Psychiatry, 2010, 67(7): 739
27. [27]
  [27] Pannee J, Portelius E, Oppermann M, et al. J Alzheimers Dis, 2013, 33(4): 1021
28. [28]
  [28] Elschenbroich S, Ignatchenko V, Clarke B, et al. J Proteome Res, 2011, 10(5): 2286
29. [29]
  [29] Addona T A, Shi X, Keshishian H, et al. Nat Biotechnol, 2011, 29(7): 635
30. [30]
  [30] Eissler C L, Bremmer S C, Martinez J S, et al. Anal Biochem, 2011, 418(2): 267
31. [31]
  [31] Zhao Y, Jia W, Wang J F, et al. Anal Chem, 2011, 83(22): 8802
32. [32]
  [32] Zhang K L, Schrag M, Crofton A, et al. Proteomics, 2012, 12(8): 1261
33. [33]
  [33] Redding-Johanson A M, Batth T S, Chan R, et al. Metab Eng, 2011, 13(2): 194
34. [34]
  [34] Pandhal J, Ow S Y, Noirel J, et al. Biotechnol Bioeng, 2011, 108(4): 902
35. [35]
  [35] Zhao Y X, Brasier A R. Methods, 2013, 61(3): 313
36. [36]
  [36] Zhao Y X, Tian B, Edeh C B, et al. Mol Cell Proteomics, 2013, 12(6), DOI: 10.1074/mcp. M112.023465
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