Citation: SHANG Chang-Shuai, LI Jing, WANG Er-Kang, GUO Shao-Jun. Recent Progress in Noble Metal Based Nanozymes for Bio-detection Application[J]. Chinese Journal of Analytical Chemistry, ;2023, 51(5): 652-665. doi: 10.19756/j.issn.0253-3820.231044 shu

Recent Progress in Noble Metal Based Nanozymes for Bio-detection Application

1.
School of Materials Science and Engineering, Peking University, Beijing 100871, China;
2.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

Corresponding author: LI Jing, GUO Shao-Jun,
Received Date: 10 February 2023
Revised Date: 30 March 2023

Fund Project: Supported by the National Natural Science Foundation of China (Nos. 52025133, 22105007), the National Key R&D Program of China (No. 2019YFA0709202), the Tencent Foundation through the XPLORER PRIZE, the Beijing Natural Science Foundation (No. JQ18005), the Fund of the State Key Laboratory of Solidification Processing in NWPU (No. SKLSP202004), the Youth Innovation Promotion Association, Chinese Academy of Sciences (No. 202055) and the China Postdoctoral Science Foundation (No. 2020M670018).

In comparison with natural enzymes, nanozymes show many advantages such as high stability, ease to mass production and tunable enzymatic properties and possess great potentials for application in detection and biosensing fields. Especially, noble metal based nanozymes usually exhibit superior catalytic activity and stability. The achievements in precisely synthesizing noble metal-based nanomaterials at atomic levels enable investigation of interaction mechanisms between structures and enzymatic performances. In this review, the development of noble metal based nanozymes were sumarized, including noble metal nanocrystals and noble metal based singleatom nanozymes. The preparation strategies, regulation methods of enzymatic properties and underlying mechanisms were mainly discussed. The applications for detection and biosensing were also elucidated. At last, the challenges and prospects of this area were briefly discussed.
- Nanozymes,
- Noble metal,
- Single-atom,
- Detection,
- Review
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