Citation: HU Zhen-Zhen, LI Xiao-Tong, LI Xiao-Dong, ZHANG Hua, LIU Gui-Feng, WANG Zhen-Xin. Applications of Peptide Functionalized Gold Nanoparticles in Bioanalysis and Biomedicine[J]. Chinese Journal of Analytical Chemistry, ;2023, 51(5): 681-694. doi: 10.19756/j.issn.0253-3820.221631 shu

Applications of Peptide Functionalized Gold Nanoparticles in Bioanalysis and Biomedicine

1.
Department of Radiology, China-Japan Union Hospital of Jilin University, Changchun 130033, China;
2.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;
3.
School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230026, China

Corresponding author: LIU Gui-Feng, WANG Zhen-Xin,
Received Date: 21 December 2022
Revised Date: 14 February 2023

Fund Project: Supported by the Jilin Provincial Science and Technology Department (No. 20220203113SF), the National Natural Science Foundation of China (Nos. 52275006, 21974133) and the Wu Jieping Medical Foundation (No. 320.6750.19089-40).

The functionalization of gold nanoparticle (GNP) surface with specific ligand is helpful to improve the bioanalysis performance of GNP and realize special application of GNP in biomedicine. Because it is easy to integrate various functions including specific biorecognition and therapeutic function into one sequence, peptides become one of the most common ligands for functionalization of GNP. The peptide functionalized GNPs (GNP@peptides) have been extensively used to build biosensing nanoplatforms with high sensitivity and selectivity for detecting various analytes (such as heavy metal ions, biomarkers, etc.) and novel therapeutic/drug delivery nanosystems with excellent anti-tumor and/or antibacterial capabilities. This review provided an overview of the effect of GNP@peptides on the precision diagnostics and therapy of diseases, and discussesed the current challenges and future prospects of GNP@peptide-based biosensing nanoplatforms and nanomedicines in practical applications.
- Peptide ligand,
- Gold nanoparticles,
- Biosensing nanoplatforms,
- Nanomedicines,
- Review
1. [1]
  MIRKIN C A, LETSINGER R L, MUCIC R C, STORHOFF J J. Nature, 1996, 382(6592):607-609.
2. [2]
  ZHANG Y, ZHANG C, XU C, WANG X, LIU C, WATERHOUSE G I N, WANG Y, YIN H. Talanta, 2019, 200:432-442.
3. [3]
4. [4]
  LIU X, ZHANG Q, KNOLL W, LIEDBERG B, WANG Y. Adv. Mater., 2020, 32(37):2000866.
5. [5]
  LIU Y, BHATTARAI P, DAI Z, CHEN X. Chem. Soc. Rev., 2019, 48(7):2053-2108.
6. [6]
  ZHOU R, ZHANG M, XI J, LI J, MA R, REN L, BAI Z, QI K, LI X. Nanoscale Res. Lett., 2022, 17(1):68.
7. [7]
  ZHANG P, CUI Y, ANDERSON C F, ZHANG C, LI Y, WANG R, CUI H. Chem. Soc. Rev., 2018, 47(10):3490-3529.
8. [8]
  DESALE K, KUCHE K, JAIN S. Biomater. Sci., 2021, 9(4):1153-1188.
9. [9]
  LI X, WANG J, SUN L, WANG Z. Chem. Commun., 2010, 46(6):988-990.
10. [10]
  INNOCENTI R, DALLARI C, LENCI E, PAVONE F S, BIANCHINI F, CREDI C, TRABOCCHI A. Bioorg. Chem., 2022, 126:105873.
11. [11]
  HU J, YUAN X, WANG F, GAO H, LIU X, ZHANG W. Chin. Chem. Lett., 2021, 32(4):1341-1347.
12. [12]
  MORSHED R A, MUROSKI M E, DAI Q, WEGSCHEID M L, AUFFINGER B, YU D, HAN Y, ZHANG L, WU M, CHENG Y, LESNIAK M S. Mol. Pharm., 2016, 13(6):1843-1854.
13. [13]
  DERAEDT C, SALMON L, GATARD S, CIGANDA R, HERNANDEZ R, RUIZ J, ASTRUC D. Chem. Commun., 2014, 50(91):14194-14196.
14. [14]
  TURKEVICH J, STEVENSON P C, HILLIER J. Discuss. Faraday Soc., 1951, 11:55-75.
15. [15]
  FRENS G. Nat. Phys. Sci., 1973, 241(105):20-22.
16. [16]
  JANA N R, GEARHEART L, MURPHY C J. J. Phys. Chem. B, 2001, 105(19):4065-4067.
17. [17]
  LÉVY R, THANH N T K, DOTY R C, HUSSAIN I, NICHOLS R J, SCHIFFRIN D J, BRUST M, FERNIG D G. J. Am. Chem. Soc., 2004, 126(32):10076-10084.
18. [18]
  OZCELIK S, PRATX G. Nanotechnology, 2020, 31(41):415102.
19. [19]
  CHIANG T H, HSIAO H H. Talanta, 2023, 253:123913.
20. [20]
  BEIDERMAN M, ASHKENAZY A, SEGAL E, BARNOY E A, MOTIEI M, SADAN T, SALOMON A, RAHIMIPOUR S, FIXLER D, POPOVTZER R. ACS Appl. Nano Mater., 2020, 3(8):8414-8423.
21. [21]
  LUO J, CHENG Y, GONG Z W, WU K, ZHOU Y, CHEN H X, GAUTHIER M, CHENG Y Z, LIANG J, ZOU T. Langmuir, 2020, 36(2):600-608.
22. [22]
  HU B, KONG F, GAO X, JIANG L, LI X, GAO W, XU K, TANG B. Angew. Chem. Int. Ed., 2018, 57(19):5306-5309.
23. [23]
  GUO W, GAO X, ZHAN R, ZHAO Z, XU K, TANG B. Talanta, 2021, 222:121525.
24. [24]
  LIU B, LI J, ZHOU P, PAN W, LI N, TANG B. Anal. Chem., 2021, 93(50):16880-16886.
25. [25]
  BARTCZAK D, KANARAS A G. Langmuir, 2011, 27(16):10119-10123.
26. [26]
  RUFF J, HASSAN N, MORALES-ZAVALA F, STEITZ J, ARAYA E, KOGAN M J, SIMON U. J. Mater. Chem. B, 2018, 6(16):2432-2443.
27. [27]
  LIMON D, VILA S, HERRERA-OLIVAS A, VERA R, BADIA J, BALDOMA L, PLANAS M, FELIU L, PEREZ-GARCIA L. Colloids Surf., B, 2021, 197:111384.
28. [28]
  LEMOINE P, DOOLEY C, MORELLI A, HARRISON E, DIXON D. Appl. Surf. Sci., 2022, 574:151386.
29. [29]
  YU Y, LUO Z, YU Y, LEE J Y, XIE J. ACS Nano, 2012, 6(9):7920-7927.
30. [30]
  ZHANG X D, CHEN J, LUO Z, WU D, SHEN X, SONG S S, SUN Y M, LIU P X, ZHAO J, HUO S, FAN S, FAN F, LIANG X J, XIE J. Adv. Healthcare Mater., 2014, 3(1):133-141.
31. [31]
  ZHANG C, GAO X, CHEN W, HE M, YU Y, GAO G, SUN T. iScience, 2022, 25(10):105022.
32. [32]
  SI S, KOTAL A, MANDAL T K. J. Phys. Chem. C, 2007, 111(3):1248-1255.
33. [33]
  LI W, NIE Z, HE K, XU X, LI Y, HUANG Y, YAO S. Chem. Commun., 2011, 47(15):4412-4414.
34. [34]
  BARTL J, REINKE L, KOCH M, KUBIK S. Chem. Commun., 2020, 56(72):10457-10460.
35. [35]
  KORKMAZ N, HWANG C, KESSLER K K, SILINA Y E, MÜLLER L, PARK J. Talanta, 2021, 232:122439.
36. [36]
  LI X Y, ZHANG M M, ZHOU X D, HU J M. Anal. Biochem., 2021, 631:114369.
37. [37]
  ZHANG W, XI J, ZHANG Y, SU Z, WEI G. Arabian J. Chem., 2020, 13(1):1406-1414.
38. [38]
  FENG S, SHI R, XU P, BHAMORE J R, BAL J, BAEK S H, PARK C Y, PARK J P, PARK T J. New J. Chem., 2020, 44(37):15828-15835.
39. [39]
  WU X, YIN J, LIU J, GU Y, WANG S, WANG J. Analyst, 2020, 145(22):7234-7241.
40. [40]
  WU A, DING H, ZHANG W, RAO H, WANG L, CHEN Y, LU C, WANG X. Food Chem., 2021, 363:130325.
41. [41]
  FENG T, GAO S, WANG K. Acta Chim. Sin., 2019, 77(5):422-426.
42. [42]
  KAKKAR S, CHAUHAN S, BALA R, BHARTI R, KUMAR V, ROHIT M, BHALLA V. Microchim. Acta, 2022, 189(10):366.
43. [43]
  WANG Z, LÉVY R, FERNIG D G, BRUST M. J. Am. Chem. Soc., 2006, 128(7):2214-2215.
44. [44]
  MAO X X, LI Y F, HAN P, WANG X H, YANG S Q, ZHANG F, GONG X Q, CAO Y. Sens. Actuators, B, 2018, 267:336- 341.
45. [45]
  LOYNACHAN C N, SOLEIMANY A P, DUDANI J S, LIN Y, NAJER A, BEKDEMIR A, CHEN Q, BHATIA S N, STEVENS M M. Nat. Nanotechnol., 2019, 14(9):883-890.
46. [46]
  HE M Q, CHEN S, YAO K, MENG J, WANG K, YU Y L, WANG J H. Anal. Chem., 2020, 92(1):1395-1401.
47. [47]
  LI X, ZHU Q, XU F, JIAN M, YAO C, ZHANG H, WANG Z. Anal. Biochem., 2022, 648:114671.
48. [48]
  CREYER M N, JIN Z, MOORE C, YIM W, ZHOU J, JOKERST J V. ACS Appl. Mater. Interfaces, 2021, 13(38):45236- 45243.
49. [49]
  JIN Z C, MANTRI Y, RETOUT M, CHENG Y, ZHOU J J, JORNS A, FAJTOVA P, YIM W, MOORE C, XU M, CREYER M N, BORUM R M, ZHOU J C, WU Z H, HE T Y, PENNY W F, O'DONOGHUE A J, JOKERST J V. Angew. Chem. Int. Ed., 2022, 61(9):e202112995.
50. [50]
  JIN Z, YEUNG J, ZHOU J, CHENG Y, LI Y, MANTRI Y, HE T, YIM W, XU M, WU Z, FAJTOVA P, CREYER M N, MOORE C, FU L, PENNY W F, O'DONOGHUE A J, JOKERST J V. Chem. Mater., 2022, 34(3):1259-1268.
51. [51]
  JIN Z, LING C, LI Y, ZHOU J, LI K, YIM W, YEUNG J, CHANG Y C, HE T, CHENG Y, FAJTOVÁ P, RETOUT M, O'DONOGHUE A J, JOKERST J V. Nano Lett., 2022, 22(22):8932-8940.
52. [52]
  GARLAND G D, HARVEY R F, MULRONEY T E, MONTI M, FULLER S, HAIGH R, GERBER P P, BARER M R, MATHESON N J, WILLIS A E. Biochem. J., 2022, 479(8):901-920.
53. [53]
  CHEN Q, ZHANG L, FENG Y, SHI F, WANG Y, WANG P, LIU L. J. Mater. Chem. B, 2018, 6(46):7643-7651.
54. [54]
  XIONG L H, HUANG S, HUANG Y, YIN F, YANG F, ZHANG Q, CHENG J, ZHANG R, HE X. ACS Appl. Mater. Interfaces, 2020, 12(11):12525-12532.
55. [55]
  LEE J I, JANG S C, CHUNG J, CHOI W K, HONG C, AHN G R, KIM S H, LEE B Y, CHUNG W J. Sens. Actuators, B, 2021, 327:128894.
56. [56]
  ZHU Q, ZHOU X. J. Hazard. Mater., 2022, 425:127923.
57. [57]
  GAO L, LIU M, MA G, WANG Y, ZHAO L, YUAN Q, GAO F, LIU R, ZHAI J, CHAI Z, ZHAO Y, GAO X. ACS Nano, 2015, 9(11):10979-10990.
58. [58]
  FENG J, HUANG P, SHI S, DENG K Y, WU F Y. Anal. Chim. Acta, 2017, 967:64-69.
59. [59]
  FU M, LI L, YANG D, TU Y, YAN J. Spectrochim. Acta, Part A, 2022, 279:121450.
60. [60]
  LI Y, DENG Y, ZHOU X, HU J. Talanta, 2018, 179:742-752.
61. [61]
  XUE F, QU F, HAN W, XIA L, YOU J. Anal. Chim. Acta, 2019, 1046:170-178.
62. [62]
  WU Y, GAO Y, DU J. Talanta, 2019, 197:599-604.
63. [63]
  WANG M K, LIU Y, SU D D, CHEN J Y, SU X G. Sens. Actuators, B, 2019, 290:512-519.
64. [64]
  WANG H, DA L, YANG L, CHU S, YANG F, YU S, JIANG C. J. Hazard. Mater., 2020, 392:122506.
65. [65]
  XIE M, WANG Y, LIU L, WANG X, JIANG H. J. Colloid Interface Sci., 2022, 614:502-510.
66. [66]
  BHAMORE J R, GUL A R, CHAE W S, KIM K W, LEE J S, PARK H, KAILASA S K, PARK T J. Sens. Actuators, B, 2020, 322:128603.
67. [67]
  QI S, SAAD AL-MASHRIQI H, SALAH A, ZHAI H. Microchem. J., 2022, 175:107163.
68. [68]
  QU F, WANG Z, LI C, JIANG D F, ZHAO X E. Sens. Actuators, B, 2022, 359:131610.
69. [69]
  QIAN D, WANG Z, XIAO Z, FANG C J. Inorg. Chem. Commun., 2021, 126:108471.
70. [70]
  YU F, CAO Z, HE S, XIANG H, ZHAO G, YANG L, LIU H. Chem. Commun., 2022, 58(6):811-814.
71. [71]
  WANG M K, WANG L, LIU Q, SU X G. Sens. Actuators, B, 2018, 256:691-698.
72. [72]
  ZHANG D, MENG Y, ZHANG C. Chem. Commun., 2020, 56(2):213-216.
73. [73]
  HE S, KYAW Y M E, TAN E K M, BEKALE L, KANG M W C, KIM S S Y, TAN I, LAM K P, KAH J C Y. Anal. Chem., 2018, 90(10):6071-6080.
74. [74]
  HUANG X, YIN Y, WU M, ZAN W, YANG Q. Chin. Chem. Lett., 2019, 30(6):1335-1340.
75. [75]
  SLOAN-DENNISON S, BEVINS M K R, SCARPITTI B T, SAUVÉ V K, SCHULTZ Z D. Analyst, 2019, 144(18):5538- 5546.
76. [76]
  ZHAO C, QIU L, LV P, HAN A, FANG G, LIU J, WANG S. Analyst, 2019, 144(4):1275-1281.
77. [77]
  JIANG Q Y, CUI X, SUN Y, MAO Z, WANG J, CHEN F, WANG J, CAO Y. Biosens. Bioelectron., 2021, 192:113539.
78. [78]
  SUN Y, WANG Y, LU W, LIU C, GE S, ZHOU X, BI C, CAO X. J. Mater. Chem. B, 2021, 9(2):381-391.
79. [79]
  ZHU W, WANG C Y, HU J M, SHEN A G. Anal. Chem., 2021, 93(11):4876-4883.
80. [80]
  YE Y, GE Y, ZHANG Q, YUAN M, CAI Y, LI K, LI Y, XIE R, XU C, JIANG D, QU J, LIU X, WANG Y. Adv. Sci., 2022, 9(12):2104738.
81. [81]
  LIU L, CHU H, YANG J, SUN Y, MA P, SONG D. Biosens. Bioelectron., 2022, 212:114389.
82. [82]
  ZHONG Q, ZHANG K, HUANG X, LU Y, ZHAO J, HE Y, LIU B. Biosens. Bioelectron., 2022, 207:114194.
83. [83]
  XING T, QIAN Q, YE H, WANG Z, JIN Y, ZHANG N, WANG M, ZHOU Y, GAO X, WU L. Biosens. Bioelectron., 2022, 212:114430.
84. [84]
  WANG J, DONG B, CHEN B, JIANG Z, SONG H. Dalton Trans., 2012, 41(36):11134-11144.
85. [85]
  ZHAO X, YANG C X, CHEN L G, YAN X P. Nat. Commun., 2017, 8(1):14998.
86. [86]
  ALI M R K, WU Y, TANG Y, XIAO H P, CHEN K C, HAN T G, FANG N, WU R H, EL-SAYED M A. Proc. Natl. Acad. Sci. U. S. A., 2017, 114(28):E5655-E5663.
87. [87]
  HA J H, SHIN H H, CHOI H W, LIM J H, MO S J, AHRBERG C D, LEE J M, CHUNG B G. Lab Chip, 2020, 20(18):3354-3364.
88. [88]
  TAN H, HUANG Y, XU J, CHEN B, ZHANG P, YE Z, LIANG S, XIAO L, LIU Z. Theranostics, 2017, 7(12):3168-3178.
89. [89]
  WU L, LIN B, YANG H, CHEN J, MAO Z, WANG W, GAO C. Acta Biomater., 2019, 86:363-372.
90. [90]
  JIN X, YANG H, MAO Z, WANG B. J. Colloid Interface Sci., 2021, 601:714-726.
91. [91]
  HA M, NAM S H, SIM K, CHONG S E, KIM J, KIM Y, LEE Y, NAM J M. Nano Lett., 2021, 21(1):731-739.
92. [92]
  GONCALVES D P N, PARK D M, SCHMIDT T L, WERNER C. Biomater. Sci., 2018, 6(5):1140-1146.
93. [93]
  SANKARI S S, URADE R, CHIU C C, WANG L F. Pharmaceutics, 2022, 14(9):1939.
94. [94]
  JABIR M S, ABOOD N A, JAWAD M H, ÖZTÜRK K, KADHIM H, ALBUKHATY S, AL-SHAMMARI A, ALMALKI F A, ALBAQAMI J, SULAIMAN G M. Mater. Tech., 2022, 37(14):3152-3166.
95. [95]
  BIAN Z, YAN J, WANG S, LI Y, GUO Y, MA B, GUO H, LEI Z, YIN C, ZHOU Y, LIU M, TAO K, HOU P, HE W. Theranostics, 2018, 8(19):5320-5335.
96. [96]
  YIN X, YANG B, CHEN B, HE M, HU B. Anal. Chem., 2019, 91(16):10596-10603.
97. [97]
  HE K, ZHU J, GONG L, TAN Y, CHEN H, LIANG H, HUANG B, LIU J. Nano Res., 2021, 14(4):1087-1094.
98. [98]
  FARHANGI S, KARIMI E, KHAJEH K, HOSSEINKHANI S, JAVAN M. Nanomed.-Nanotechnol. Biol. Med., 2023, 47:102609.
99. [99]
  LIU B, QIAO G, HAN Y, SHEN E, ALFRANCA G, TAN H, WANG L, PAN S, MA L, XIONG W, LIU Y, CUI D. Acta Biomater., 2020, 117:361-373.
100. [100]
  LIU Z, XIE F, XIE J, CHEN J, LI Y, LIN Q, LUO F, YAN J. Drug Delivery, 2021, 28(1):1769-1784.
101. [101]
  HOU G H, QIAN J M, XU W J, SUN T T, WANG J L, WANG Y P, SUO A L. Colloids Surf., B, 2019, 181:602-611.
102. [102]
  HUANG S H, PENG S, WANG Q Y, HU Q H, ZHANG R Q, LIU L, LIU Q, LIN J, ZHOU Q H. Colloids Surf., B, 2021, 207:112014.
103. [103]
  LIU X, LIU J, XU S, LI X, WANG Z, GAO X, TANG B, XU K. ACS Appl. Mater. Interfaces, 2023, 15(2):2529-2537.
104. [104]
  YE L, CHEN Y, MAO J, LEI X, YANG Q, CUI C. J. Exp. Clin. Cancer Res., 2021, 40(1):303.
105. [105]
  PENG J, WANG R, SUN W, HUANG M, WANG R, LI Y, WANG P, SUN G, XIE S. Biomater. Sci., 2021, 9(19):6528- 6541.
106. [106]
  TANG W, HAN L, LU X, WANG Z, LIU F, LI Y, LIU S, LIU S, TIAN R, LIU J, DING B. ACS Appl. Mater. Interfaces, 2021, 13(18):20974-20981.
107. [107]
  ZHANG M, LIN J, JIN J, YU W, QI Y, TAO H. Front. Pharmacol., 2021, 12:799588.
108. [108]
  CHAKABORTY K, BISWAS A, MISHRA S, MALLICK A M, TRIPATHI A, JAN S, ROY R S. ACS Appl. Bio Mater., 2023, 6(2):458-472.
109. [109]
  TIAN D, QIN F, ZHAO H, ZHANG C, WANG H, LIU N, AI Y. Colloids Surf., B, 2021, 202:111681.
110. [110]
  VUKOMANOVIC M, CENDRA M D, BAELO A, TORRENTS E. Colloids Surf., B, 2021, 208:112083.
111. [111]
  ZHENG Y K, LIU W W, CHEN Y, LI C M, JIANG H, WANG X M. J. Colloid Interface Sci., 2019, 546:1-10.
112. [112]
  SANKARI S S, DAHMS H U, TSAI M F, LO Y L, WANG L F. Colloids Surf., B, 2021, 208:112117.
113. [113]
  SHENG G, NI J, XING K, FAN L, DAI T, YU J, DAI X, CHEN R, WU J, LI N, CHEN J, MAO Z, LI L. Colloid Interface Sci. Commun., 2021, 41:100379.
114. [114]
  XU X Y, DING Y J, HADIANAMREI R, LV S W, YOU R R, PAN F, ZHANG P, WANG N, ZHAO X B. Colloids Surf., B, 2022, 220:112887.
115. [115]
  DONG X, YE J, CHEN Y, TANZIELA T, JIANG H, WANG X. Chem. Eng. J., 2022, 432:134061.
1. [1]
  Yu Dai , Xueting Sun , Haoyu Wu , Naizhu Li , Guoe Cheng , Xiaojin Zhang , Fan Xia . Determination of the Michaelis Constant for Gold Nanozyme-Catalyzed Decomposition of Hydrogen Peroxide. University Chemistry, 2025, 40(5): 351-356. doi: 10.12461/PKU.DXHX202407052
2. [2]
  Lina Liu , Xiaolan Wei , Jianqiang Hu . Exploration of Subject-Oriented Undergraduate Comprehensive Chemistry Experimental Teaching Based on the “STS Concept”: Taking the Experiment of Gold Nanoparticles as an Example. University Chemistry, 2024, 39(10): 337-343. doi: 10.12461/PKU.DXHX202405112
3. [3]
  Yongming Guo , Jie Li , Chaoyong Liu . Green Improvement and Educational Design in the Synthesis and Characterization of Silver Nanoparticles. University Chemistry, 2024, 39(3): 258-265. doi: 10.3866/PKU.DXHX202309057
4. [4]
  Jie WEI , Qing ZHOU , Dandan DING , Xiang JING , Fei LI . Photothermal toxicity of Prussian blue nanoparticles to cervical cancer cells. Chinese Journal of Inorganic Chemistry, 2025, 41(11): 2345-2357. doi: 10.11862/CJIC.20240435
5. [5]
  Gaopeng Liu , Lina Li , Bin Wang , Ningjie Shan , Jintao Dong , Mengxia Ji , Wenshuai Zhu , Paul K. Chu , Jiexiang Xia , Huaming Li . Construction of Bi Nanoparticles Loaded BiOCl Nanosheets Ohmic Junction for Photocatalytic CO₂ Reduction. Acta Physico-Chimica Sinica, 2024, 40(7): 2306041-0. doi: 10.3866/PKU.WHXB202306041
6. [6]
  Ruifeng CHEN , Chao XU , Jianting JIANG , Tianshe YANG . Gold nanorod/zinc oxide/mesoporous silica nanoplatform: A triple-modal platform for synergistic anticancer therapy. Chinese Journal of Inorganic Chemistry, 2025, 41(11): 2272-2282. doi: 10.11862/CJIC.20250117
7. [7]
  Yang Meiqing , Lu Wang , Haozi Lu , Yaocheng Yang , Song Liu . Recent Advances of Functional Nanomaterials for Screen-Printed Photoelectrochemical Biosensors. Acta Physico-Chimica Sinica, 2025, 41(2): 100018-0. doi: 10.3866/PKU.WHXB202310046
8. [8]
  Lin LI , Jiaxue LI , Meixia YANG , Jiayu DING , Jiaqi JING , Ruiping ZHANG . Preparation of mitoxantrone self-assembled carrier-free nanodrugs regulated by sodium acetate for apoptosis induction of human breast carcinoma cells. Chinese Journal of Inorganic Chemistry, 2025, 41(12): 2536-2548. doi: 10.11862/CJIC.20250138
9. [9]
  Zijuan LI , Xuan LÜ , Jiaojiao CHEN , Haiyang ZHAO , Shuo SUN , Zhiwu ZHANG , Jianlong ZHANG , Yanling MA , Jie LI , Zixian FENG , Jiahui LIU . Synthesis of visual fluorescence emission CdSe nanocrystals based on ligand regulation. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 308-320. doi: 10.11862/CJIC.20240138
10. [10]
  Hong LI , Xiaoying DING , Cihang LIU , Jinghan ZHANG , Yanying RAO . Detection of iron and copper ions based on gold nanorod etching colorimetry. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 953-962. doi: 10.11862/CJIC.20230370
11. [11]
  Ruiqin Feng , Ye Fan , Yun Fang , Yongmei Xia . Strategy for Regulating Surface Protrusion of Gold Nanoflowers and Their Surface-Enhanced Raman Scattering. Acta Physico-Chimica Sinica, 2024, 40(4): 2304020-0. doi: 10.3866/PKU.WHXB202304020
12. [12]
  Hongpeng He , Mengmeng Zhang , Mengjiao Hao , Wei Du , Haibing Xia . Synthesis of Different Aspect-Ratios of Fixed Width Gold Nanorods. Acta Physico-Chimica Sinica, 2024, 40(5): 2304043-0. doi: 10.3866/PKU.WHXB202304043
13. [13]
  Huihui LIU , Baichuan ZHAO , Chuanhui WANG , Zhi WANG , Congyun ZHANG . Green synthesis of MIL-101/Au composite particles and their sensitivity to Raman detection of thiram. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 2021-2030. doi: 10.11862/CJIC.20240059
14. [14]
  Jinghan ZHANG , Guanying CHEN . Progress in the application of rare-earth-doped upconversion nanoprobes in biological detection. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2335-2355. doi: 10.11862/CJIC.20240249
15. [15]
  Dingwen CHEN , Siheng YANG , Haiyan FU , Hua CHEN , Xueli ZHENG , Weichao XUE , Jiaqi XU , Ruixiang LI . NiOOH-mediated synthesis of gold nanoaggregates for electrocatalytic performance for selective oxidation of glycerol to glycolate. Chinese Journal of Inorganic Chemistry, 2025, 41(11): 2317-2326. doi: 10.11862/CJIC.20250053
16. [16]
  Ling WANG , Weipeng YAN , Zhuoyi ZHENG , Sihan ZHU , Mingxian GONG , Xiangyu MA . Fabrication of biochar-supported nano zero-valent iron and its high-efficiency performance for Cr(Ⅵ) removal from wastewater. Chinese Journal of Inorganic Chemistry, 2025, 41(12): 2441-2454. doi: 10.11862/CJIC.20250264
17. [17]
  Gaofeng Zeng , Shuyu Liu , Manle Jiang , Yu Wang , Ping Xu , Lei Wang . Micro/Nanorobots for Pollution Detection and Toxic Removal. University Chemistry, 2024, 39(9): 229-234. doi: 10.12461/PKU.DXHX202311055
18. [18]
  Xiaoyu YANG , Yejun ZHANG , Yu ZOU , Hongchao YANG , Jiang JIANG , Qiangbin WANG . Research progress of inorganic X-ray nanoscintillators. Chinese Journal of Inorganic Chemistry, 2025, 41(10): 1929-1952. doi: 10.11862/CJIC.20250122
19. [19]
  Lijun Yue , Siya Liu , Peng Liu . 不同晶相纳米MnO₂的制备及其对生物乙醇选择性氧化催化性能的测试——一个科研转化的综合化学实验. University Chemistry, 2025, 40(8): 225-232. doi: 10.12461/PKU.DXHX202410005
20. [20]
  Yang Li , Jiachen Li , Daidi Fan . 二硫化钼纳米片的制备及其纳米酶性能探究——介绍一个大学化学综合实验. University Chemistry, 2025, 40(8): 233-240. doi: 10.12461/PKU.DXHX202410016

Get Citation

PDF

XML

Metrics

PDF Downloads(9)
Abstract views(3498)
HTML views(104)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142