Citation: RAO Hong-Hong, LIU Hai-Xia, LUO Ming-Yue, XUE Xin, WEI Ming-Ming, XUE Zhong-Hua. Progress of Simple Signal Readout-based Point-of-Care Testing[J]. Chinese Journal of Analytical Chemistry, ;2021, 49(1): 1-13. doi: 10.19756/j.issn.0253-3820.201346 shu

Progress of Simple Signal Readout-based Point-of-Care Testing

1.
College of Chemistry & Chemical Engineering, Lanzhou City University, Lanzhou 730070, China;
2.
College of Chemistry & Chemical Engineering, Northwest Normal University, Lanzhou 730070, China

Corresponding author: RAO Hong-Hong, rhh@nwnu.edu.cn
Received Date: 14 June 2020
Revised Date: 1 September 2020

Fund Project: Supported by the National Natural Science Foundation of China (Nos. 21765013, 21665023), and the Research Projects of Universities in Gansu Province, China (No. 2017A-115).

As a kind of convenient, fast and the online analysis technology, point-of-care testing (POCT) technology has been widely used in disease diagnosis, health management, environmental monitoring and emergency response analysis. To date, it is a hot spot to develop novel strategy for the detection of various targets based on the simple, rapid and sensitive signal readout and different signal production, transfer and amplification strategies in the field of POCT. The introduction of some nanozymes and functionalized nanomaterials with special catalytic properties further accelerates the application of simple analysis signal readout such as color, temperature, pressure, weight and distance, which greatly promotes the development of simple readout-based POCT methods, and expands the analytical application of such methods. In this paper, we summarize the principles, classifications and the applications of these emerging POCT methods for the analysis of life-related targets and review their current challenges and future application prospects.
- Point-of-care testing,
- Simple signal readout,
- Rapid detection,
- Review
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沈阳化工大学材料科学与工程学院沈阳 110142