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Citation: GUI Jian-Ye, ZHANG Jing, ZHANG Chen-Ling, CHEN Zong-Yu, LIU Fei, CHEN Huan-Wen. Approach to Compound-Specific Isotope Analysis of Chlorine with Reaction Mass Spectrometry and its Exploration[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(2): 237-243. doi: 10.19756/j.issn.0253-3820.181544 shu

Approach to Compound-Specific Isotope Analysis of Chlorine with Reaction Mass Spectrometry and its Exploration

1.
Institute of Hydrogeology and Environmental Geology, Chinese Academy of Geological Sciences, Zhengding 050803, China;
2.
School of Water Resources and Environment, China University of Geoscience, Beijing 100083, China;
3.
Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang 330013, China

Received Date: 20 August 2018
Revised Date: 12 December 2018

Fund Project: This study was supported by the Fundamental Research Funds of Chinese Academy of Geosciences(No.YYWF201625), the Natural Science Foundation of Hebei Province (No. B201704001) and the Fundation of Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation(No.JXMS201509).

Reaction mass spectrometry can provide specific information through the introduction of reactive gas into ionization source. A new compound-specific stable chlorine isotope analysis (CSIA-Cl) method was developed to overcome drawbacks of existing methods. Contemporary methods often require laborious off-line procedures prior to isotope analysis to obtain the chlorine isotope ratios from the mass spectra. In contrast to previous methods, our on-line setup was based on the use of chemical ionisation mass spectrometry through the introduction of methane. The cleanest ion traces of ³⁵Cl^-(m/z 35) and ³⁷Cl^-(m/z 37) were recorded to directly determine the isotopic ratios of chlorine and the method completely avoided isobaric interferences. The stable chlorine fragments were obtained from each specific chlorinated compound using the appropriate energy and an optimized acquisition mode, and the precision was maintained by the control of reactive gas flow and filament current. The principle and the mechanism of this method were presented and explained using trichloroethylene (TCE) and perchloroethylene(PCE). Method validation was investigated using chlorinated alkenes, chlorinated benzenes, and organochlorine pesticides. The sensitivity of the method was significantly improved, and standard deviations (1σ) was almost below 2.0‰. Further reaction mass spectrometry scheme was proposed in order to improve the precision, which offered an innovative approach to compound-specific chlorine isotope analysis, and it could facilitate the application of CSIA-Cl in many fields.
- Reaction mass spectrometry,
- Compound-specific stable isotope analysis,
- Chlorinated Compounds,
- Isobaric interference,
- Groundwater,
- Nonaqueous-phase liquids
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