Citation: Lin WANG, Xiao-Feng WANG, Meng-Wei XUE, Shu-Rong DUAN, Ting LI, Zhen-Zhen YU, Dun-Lin ZHANG. Synthesis, Crystal Structure and Fe³⁺ Recognition of a Fluorescent Probe Based on Quinazolinone Derivative[J]. Chinese Journal of Structural Chemistry, ;2022, 41(3): 220305. doi: 10.14102/j.cnki.0254-5861.2011-3325 shu

Synthesis, Crystal Structure and Fe³⁺ Recognition of a Fluorescent Probe Based on Quinazolinone Derivative

a.
School of Environmental Science, Nanjing Xiaozhuang University, Nanjing 211171, China
b.
School of Food Science, Nanjing Xiaozhuang University, Nanjing 211171, China

Corresponding author: Dun-Lin ZHANG, zdlocean@aliyun.com
Received Date: 9 August 2021
Accepted Date: 15 October 2021

Figures(7)

A novel quinazolinone derivative ethyl 2-(2-methyl-4-oxo-1, 2, 3, 4-tetrahydroquinazolin-2-yl) acetate (EMOTA) was synthesized and characterized by HRMS, ¹H NMR, ¹³C NMR spectroscopy and X-ray crystallography, and the ion recognition performance of the compound was studied by fluorescence analysis measurements. The results showed that probe EMOTA has a rapid fluorescence response, good selectivity and sensitivity to Fe³⁺. When the concentration of Fe³⁺ was in the range of 0~10.0 × 10^-5 mol/L, the fluorescence quenching could be affected by the probe, and the detection limit was 1.65 × 10^-6 mol/L. In addition, the identification and detection of Fe³⁺ in water samples were studied, and the results showed that probe EMOTA has high efficiency, significant sensitivity and high selectivity on the recognition and detection of Fe³⁺ in water samples, which indicates probe EMOTA has a practical application prospect.
- quinazolinone,
- crystal structure,
- fluorescent probe
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Synthesis, Crystal Structure and Fe3+ Recognition of a Fluorescent Probe Based on Quinazolinone Derivative

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通讯作者: 陈斌, bchen63@163.com

Synthesis, Crystal Structure and Fe³⁺ Recognition of a Fluorescent Probe Based on Quinazolinone Derivative