Citation: KONG Du-Lin, JIANG Jie, WU Lu-Yong, WANG Xiang-Hui, SHI Zai-Feng, WU Ming-Shu, WANG Xin, LIN Qiang. Synthesis, Structure and Antimicrobial Activity of 9,9-Dimethyl-9,10-dihydrospiro[benzo[a]-xanthene-12,3'-indoline]-2',11(8H)-dione[J]. Chinese Journal of Structural Chemistry, ;2016, 35(12): 1849-1854. doi: 10.14102/j.cnki.0254-5861.2011-1249 shu

Synthesis, Structure and Antimicrobial Activity of 9,9-Dimethyl-9,10-dihydrospiro[benzo[a]-xanthene-12,3'-indoline]-2',11(8H)-dione

  • Corresponding author: WU Ming-Shu, wmsh@hainuu.edu.cn WANG Xin, wangx@njust.edu.cn LIN Qiang, linqianggroup@163.com
  • Received Date: 15 April 2016
    Accepted Date: 9 August 2016

    Fund Project: Natural Science Foundation of Hainan Province 20162033Cultivation Research Foundation of Hainan Medical University HY2015-02

Figures(4)

  • One novel spiro-compound (C26H21NO3) has been synthesized and characterized by means of NMR spectroscopy, elemental analyses and X-ray diffraction. The single crystal belongs to the monoclinic system, space group P21/c with a=8.8039(7), b=24.123(2), c=10.0751(9)Å, β=108.403(3)°, Mr=395.44, V=2030.3(3)Å3, Z=4, Dc=1.294 g/cm3, F(000)=832.0, μ=0.085 mm-1, R=0.0801 and wR=0.2228. The title compound shows good activities against Micrococcus tetragenus, Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, S. albus and Escherichia coli.
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