Citation: SUN Guo-Xiang, SHI Yan-Xia, ZHAI Zhi-Wen, YANG Ming-Yan, WENG Jian-Quan, TAN Cheng-Xia, LIU Xing-Haib, LI Bao-Ju. Synthesis, Crystal Structure and Biological Activity of (E)-3-Chloro-2-(2-(2-methylbenzylidene)-hydrazinyl)pyridine[J]. Chinese Journal of Structural Chemistry, ;2016, 35(4): 640-644. doi: 10.14102/j.cnki.0254-5861.2011-0991 shu

Synthesis, Crystal Structure and Biological Activity of (E)-3-Chloro-2-(2-(2-methylbenzylidene)-hydrazinyl)pyridine

1.
a School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng, Jiangsu 224051, China;
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b College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China;
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c Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100014, China

Corresponding author: LI Bao-Ju,
Received Date: 30 September 2015
Available Online: 18 February 2016
Fund Project: This work was funded by the Natural Science Foundation of Zhejiang Province (No. LY16C140007) (No. LY16C140007)the program of Science and Technology of Jiangsu Province (BY2014108-14) (2014C31127, 2013C32SA700134)

The novel Schiff base (E)-3-chloro-2-(2-(2-methylbenzylidene)hydrazinyl)pyridine was synthesized and characterized by ¹H NMR, MS, elemental analysis and X-ray diffraction. The compound crystallizes in monoclinic space group Pbca with a=14.6638(3), b=7.7522(2), c=20.3850(4) Å, V=2317.30(9) Å³, Z=8, R=0.063 and wR=0.1922. The title compound exhibits good antifungal activity against Stemphylium lycopersici (Enjoji) Yamamoto and Fusarium oxysporum sp. cucumebrium.
- Schiff base,
- synthesis,
- crystal structure,
- antifungal activity
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