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Citation: Shuxin Li, Jingxuan Liu, Xiaoqing Qiu. When “engraved in DNA” becomes reality: exploring the cutting-edge technology of double helix data storage[J]. University Chemistry, ;2026, 41(7): 144-153. doi: 10.12461/PKU.DXHX202506092 shu

When “engraved in DNA” becomes reality: exploring the cutting-edge technology of double helix data storage

College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, Hunan Province, China

Corresponding author: Xiaoqing Qiu, xq-qiu@csu.edu.cn
Received Date: 24 June 2025
Revised Date: 29 August 2025

This article employs the popular expression “engraved in DNA” as an engaging introduction to elucidate the developmental trajectory and potential applications of DNA data storage technology. The discussion begins with the pioneering phase, detailing the encoding, synthesis, storage, and retrieval processes along with the technical limitations of early implementations. Subsequently, it highlights the innovative “Bi Sheng-1” movable-type storage inkjet printer system and the catalytic role of enzymatic synthesis in achieving automated, high-speed data writing. The paper concludes by examining practical applications in archival preservation and space exploration, while addressing accompanying ethical considerations, thereby stimulating reader interest in this frontier of chemical science.
- DNA data storage,
- Technological evolution,
- Anthropomorphic narrative,
- Prospects and challenges
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