Citation: Yujie Li, Jiayu Liu, Wenbo Liu, Tingbin Zhang, Kangyu Shen, Jia Luo, Yuan He, Mingli Peng, Xiaoli Liu, Haiming Fan. The magnetothermal strike team: chronicles of the cancer war[J]. University Chemistry, ;2026, 41(7): 219-226. doi: 10.12461/PKU.DXHX202506067 shu

The magnetothermal strike team: chronicles of the cancer war

Yujie Li ¹ ,
Jiayu Liu ¹ ,
Wenbo Liu ² ,
Tingbin Zhang ³ ,
Kangyu Shen ¹ ,
Jia Luo ¹ ,
Yuan He ¹ ,
Mingli Peng ^1,, ,
Xiaoli Liu ^4,, ,
Haiming Fan ^1,,

1.
College of Chemistry and Materials Science, Northwest University, Xi'an 710127, Shaanxi Province, China;
2.
Faculty of Liberal Arts, Northwest University, Xi'an 710127, Shaanxi Province, China;
3.
School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin 300131, China;
4.
National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China

Corresponding author: Mingli Peng, Xiaoli Liu, Haiming Fan,
Received Date: 15 June 2025
Revised Date: 29 August 2025

In humanity’s protracted battle against cancer, ferrimagnetic vortex iron oxide nanorings have recently emerged as a new generation of “precision troops” in anticancer strategies. These nanostructures combine exceptional magnetothermal properties with tunable surface functionalization, working synergistically with ferroptosis mechanisms and immunotherapy to enable multidimensional anticancer approaches. Using the metaphor of a thermal warfare campaign, this article elucidates how these diminutive yet potent nanorings demonstrate ultrahigh specific absorption rates under alternating magnetic fields while achieving precise tumor targeting through sophisticated surface design. Their capacity for rapid thermal energy release enables effective tumor destruction. Through this narrative of combined thermal and immunological warfare, we aim to introduce readers to magnetic nanomaterials in tumor hyperthermia applications and stimulate interest in innovative anticancer approaches.
- Ferrimagnetic vortex iron oxide nanorings,
- Cancer therapy,
- Magnetic hyperthermia,
- Ferroptosis,
- Immunological effects
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沈阳化工大学材料科学与工程学院沈阳 110142