Citation: Mengying Zhang, Daiqiang Fei, Xiaoqian Liu, Xiaomin Sun, Yu Bai, Yu Wang, Chade Lv, Dianpeng Qi, Lei Wang. The fabrication of liquid-metal-based micro/nano robots and their biomedical applications[J]. University Chemistry, ;2026, 41(7): 154-160. doi: 10.12461/PKU.DXHX202504080 shu

The fabrication of liquid-metal-based micro/nano robots and their biomedical applications

Mengying Zhang ¹ ,
Daiqiang Fei ² ,
Xiaoqian Liu ¹ ,
Xiaomin Sun ¹ ,
Yu Bai ³ ,
Yu Wang ¹ ,
Chade Lv ^1,, ,
Dianpeng Qi ^1,, ,
Lei Wang ^1,,

1.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, Heilongjiang Province, China;
2.
School of Mathematics, Harbin Institute of Technology, Harbin 150001, Heilongjiang Province, China;
3.
Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang Province, China

Corresponding author: Chade Lv, Dianpeng Qi, Lei Wang,
Received Date: 28 April 2025
Revised Date: 29 August 2025

Cancer remains a prevalent and challenging disease in modern society. With recent advancements in bionanotechnology, researchers have developed intelligent micro/nanomaterials known as liquid-metal-based robots. This emerging interdisciplinary technology combines biotechnology, materials science, nanoengineering, and mechanical systems. These miniature robots can undergo controlled morphological transformations under external fields, enabling targeted cancer therapy, though the technology remains relatively unknown. Drawing inspiration from the literary classic “Journey to the West”, this study employs anthropomorphic narrative techniques to elucidate the fabrication methods, deformation characteristics, and therapeutic processes of liquid-metal robots in vivo. This article aims to enhance public understanding of the scientific principles underlying these transformative biomedical agents, thereby facilitating their practical clinical applications.
- Liquid metal,
- Micro/nanorobots,
- Tumor therapy,
- Deformation mechanism,
- Actuation methods
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